DRSC/TRiP Functional Genomics Resources

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Protein Alignment DAZ1 and bol

DIOPT Version :9

Sequence 1:NP_004072.3 Gene:DAZ1 / 1617 HGNCID:2682 Length:744 Species:Homo sapiens
Sequence 2:NP_001261614.1 Gene:bol / 39049 FlyBaseID:FBgn0011206 Length:233 Species:Drosophila melanogaster


Alignment Length:282 Identity:76/282 - (26%)
Similarity:103/282 - (36%) Gaps:94/282 - (33%)


- Green bases have known domain annotations that are detailed below.


Human   347 ASTQSSSAAASQGWVLP-----EGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRT 406
            |:....||....|...|     .|.::||.:|||||.....|.::...|..||:||..|||.:|.
  Fly     5 AAAPPPSATPGGGLETPLAAPKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRA 69

Human   407 GVSKGYGFVSFVNDVDVQKIV--GSQIHFHGKKLKLGPAIRKQKLCARHVQPRPL---------- 459
            |||||||||:|..:.:.|::.  |..:....:||.:.|||:|        ||.||          
  Fly    70 GVSKGYGFVTFETEQEAQRLQADGECVVLRDRKLNIAPAIKK--------QPNPLQSIVATNGAV 126

Human   460 --VVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEY 522
              ...||.|                   |:..|:.|.  |.:.||........|...:       
  Fly   127 YYTTTPPAP-------------------ISNIPMDQF--AAAVYPPVTDFTAAGVPAI------- 163

Human   523 PTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQ--------AFPAYPNSPFQ 579
              ||.||.|           ||||..|...|..|...:.   .|||        :..:.|:||..
  Fly   164 --YPPSAMQ-----------YQPFYQYYSVPMNVPTIWP---QNYQENHSPLLHSPTSNPHSPHS 212

Human   580 VATGYQFPVYNYQPFPAYPSSP 601
                           .::|.||
  Fly   213 ---------------QSHPQSP 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DAZ1NP_004072.3 RRM_DAZL 35..116 CDD:241116
PABP-1234 42..603 CDD:130689 76/282 (27%)
RRM_DAZL 200..281 CDD:241116
RRM_DAZL 365..446 CDD:241116 35/82 (43%)
bolNP_001261614.1 RRM_DAZL_BOULE 31..111 CDD:240858 34/79 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146926
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1610446at2759
OrthoFinder 1 1.000 - - FOG0002544
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11176
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
76.910

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