Protein Alignment DAPK3 and CaMKI

DIOPT Version :9

• Sequence 1: NP_001339.1
• Gene: DAPK3 / 1613
• HGNCID: 2676
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 381
• Identity: 123/381 - (32%)
• Similarity: 191/381 - (50%)
• Gaps: 47/381 - (12%)

Human     5 RQEDVEDHYEMGEELGSGQFAIVRKCRQKGT-GKEYAAKFIKKRRLSSSRRGVSREEIEREVNIL 68
            :|..:|:.|.:...||:|.|:.||....|.: |:.:|.|.|.|:.|..     ..|.:|.|:.:|
  Fly    23 KQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKG-----KEESLENEIRVL 82

Human    69 R---------------EIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
            |               .:.||||:.|.:.:|:|:.|.|::|||:||||||.:.||.|.||.:|:.
  Fly    83 RRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASH 147

Human   119 FLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEF 183
            .::|||:.|.|:|.:.:.|.||||||::....: .:.:|.:.|||:: |:|.........|||.:
  Fly   148 LIRQILEAVDYMHEQGVVHRDLKPENLLYYSPD-DDSKIMISDFGLS-KMEDSGIMATACGTPGY 210

Human   184 VAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELA 248
            ||||::..:|.|...|:||||||:||||.|..||..|........|...:::||..|:...||.|
  Fly   211 VAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESA 275

Human   249 KDFIRRLLVKDPKRRMTIAQSLEHSWIKA--IRRRNVRG---EDSGRKPERRRLKTTRLKEYTIK 308
            |.||:.|:....::|.|..|:|.|:||..  ...||:.|   |...:...:.|.|........|:
  Fly   276 KHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIR 340

Human   309 SHSSLPPN-NSYADFER------------------FSKVLEEAAAAEEGLRELQRS 345
            ....:..| ||.|:|:.                  .|.||....:.:...:|:.:|
  Fly   341 QMQRMALNSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQEMNKS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAPK3	NP_001339.1	STKc_DAPK	7..275	CDD:271007	103/283 (36%)
		Activation segment. /evidence=ECO:0000250|UniProtKB:O96017	161..204		17/42 (40%)
		Leucine-zipper. /evidence=ECO:0000303|PubMed:9488481	427..441
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	103/280 (37%)
		S_TKc	31..302	CDD:214567	102/277 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810