Protein Alignment REM2 and rem2

DIOPT Version :9

• Sequence 1: XP_016876547.1
• Gene: REM2 / 161253
• HGNCID: 20248
• Length: 373
• Species: Homo sapiens
• Sequence 2: XP_002941555.1
• Gene: rem2 / 100488324
• XenbaseID: XB-GENE-491229
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 306
• Identity: 180/306 - (58%)
• Similarity: 221/306 - (72%)
• Gaps: 21/306 - (6%)

Human    73 LKKSEKLLA-ELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSG 136
            |.|.|||.. :..|..||.:.| ||||||||:||||||||.|||||||||  :..||||||:.|.
 Frog     3 LNKKEKLGGLQQHRGSLPLSSG-PRRRGSMPLPYKHQLRRTQAVDELDWP--SVHSGSSDSIRSS 64

Human   137 EAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVY 201
            |::|  ..|::||||:|:||||||||||.|||::....|..|:| ||||||.::||.|:.||:||
 Frog    65 ESSP--DTGVYKVMLLGDSGVGKSTLAGIFGGVEDTFPHGSEHP-EDTYERNLLVDGEKTTLIVY 126

Human   202 DIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDL 266
            ||||:..:..|::|.|||.|||||::||||||.:|.::|..||:||..|||..:|:||||||.||
 Frog   127 DIWEEAGSQSWMQDSCLQMGDAFLLIFSVTDRSTFQRLPSLLLQLRTARPHRHIPIILVGNKGDL 191

Human   267 ARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEG 331
            .|||||::||||.|||.|:||:.|.||||||||.||.||.|||||||:          |.|....
 Frog   192 VRSREVNMEEGRSLAGMLNCKYTEISAALHHNTHELLEGVVRQIRLRK----------DEGEHSL 246

Human   332 PAP----PARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL 373
            ..|    |.|||||||:|:|.|..|:.::..||||||:||||||||
 Frog   247 QTPILLTPGRRESLTKRARRLLQGLMGKHRGFFKQRSKSCHDLSVL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REM2	XP_016876547.1	None
rem2	XP_002941555.1	RGK	73..292	CDD:206715	134/229 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I13391
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11222
Inparanoid	1	1.050	348	1.000	Inparanoid score	I9876
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D254353at32523
OrthoFinder	1	1.000	-	-		FOG0013427
OrthoInspector	1	1.000	-	-		oto151496
Panther	1	1.100	-	-	LDO	PTHR45775
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R11395
SonicParanoid	1	1.000	-	-		X743
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.100