Protein Alignment CLEC14A and apx-1

DIOPT Version :9

• Sequence 1: NP_778230.1
• Gene: CLEC14A / 161198
• HGNCID: 19832
• Length: 490
• Species: Homo sapiens
• Sequence 2: NP_503882.2
• Gene: apx-1 / 178759
• WormBaseID: WBGene00000168
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 73/369 - (19%)
• Similarity: 112/369 - (30%)
• Gaps: 145/369 - (39%)

Human   131 VEEPQRSCTAR------RCAVLQATGGVEPAGWKEMR-CHLR---ANGYLCKYQFEVLCPAPRPG 185
            |.|...:|..|      ||.:             ::: |.|.   |||.:|...
 Worm   219 VNETPNTCKCRDGFIGDRCDI-------------DIKICSLEKPCANGGICSID----------- 259

Human   186 AASNLSYR--APFQLHSAALDFSPPGTEVSALCRGQLPIS-VTCIADEI----GARWDKLSGDVL 243
            ::|:..|:  .||:.             |.:.|:  .|:| |.|.|:.:    ||.......::.
 Worm   260 SSSSTGYKCHCPFEF-------------VGSQCK--TPLSKVRCSAEHVCKNGGACISMDDTNIQ 309

Human   244 CPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVPTRRPPA 308
            |.|...:  :||..|:.| ..|.....|......::..|...||.:.|        .:.|...||
 Worm   310 CKCRRGF--SGKFCEIGN-HGDCSAMRCSAGETCQISGDFAICVENDE--------LLLTTNKPA 363

Human   309 TATSPVPQRTWPIRV--DEKLGETPLVPEQDNSVTSI--------------------PEIPRWGS 351
            ..|..|.:...|.:.  ||:..:    ..|...:.:|                    ....:|..
 Worm   364 ETTKSVEKWREPRKTANDEQASD----ELQLRLIAAICVLFSVCVIGLALVSFFFYMHSFSKWKH 424

Human   352 QSTMSTLQMSLQAESKATITPSGSVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVVLVILTMT 416
            .|:        |....:||.|:.:.|..  |||||.|...
 Worm   425 PSS--------QQAGGSTILPTTTSIPM--STTSSGTGSP------------------------- 454

Human   417 VLGLVKLCFHESPSSQPRKESMG-PPGLESDPEPAALGSSSAHC 459
               :.|:|..:|       |..| .||..||.||      ..||
 Worm   455 ---VYKVCIIDS-------EHRGNAPGSSSDSEP------DHHC 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLEC14A	NP_778230.1	CLECT_thrombomodulin_like	32..175	CDD:153070	12/53 (23%)
		FXa_inhibition	254..286	CDD:291342	7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..349		13/84 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	428..461		11/33 (33%)
apx-1	NP_503882.2	DSL	108..172	CDD:302925

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161463606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930