Protein Alignment DGKQ and dgkq

DIOPT Version :10

• Sequence 1: XP_047305643.1
• Gene: DGKQ / 1609
• HGNCID: 2856
• Length: 971
• Species: Homo sapiens
• Sequence 2: XP_002935917.1
• Gene: dgkq / 733958
• XenbaseID: XB-GENE-868466
• Length: 956
• Species: Xenopus tropicalis
• Alignment Length: 997
• Identity: 576/997 - (57%)
• Similarity: 714/997 - (71%)
• Gaps: 89/997 - (8%)

Human     5 AEPGARA------WLGGGSPRPGSPACSPVLGSGGRARPGP---------------GPGPGPERA 48
            |..|||:      :.|||.....||:.||.|| ||:.|..|               ...||.:..
 Frog     2 AADGARSRFGNLGYRGGGGSSNSSPSSSPKLG-GGKIRTPPLQQRRTASPHSGSSSSSSPGAKHQ 65

Human    49 GVR-APGPAAAPGHSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVA 112
            .:: ||   .:|.|||||||||||||||.|:|||||||||.|:||||||||||||||:..|:.:|
 Frog    66 QLKQAP---FSPAHSFRKVTLTKPTFCHHCTDFIWGLAGFQCEVCNFMSHEKCLKHVKTVCSCMA 127

Human   113 PSLVRVPVAHCFGPRGLHKRKFCAVCRKVL-EAPALHCEVCELHLHPDCVPFACSDCRQCHQDGH 176
            ||||||||||||.|.|.:|:|||:||||.| |:..|.|||||||:|.||..||||||||||.||.
 Frog   128 PSLVRVPVAHCFRPPGHYKKKFCSVCRKHLEESLTLRCEVCELHVHTDCAQFACSDCRQCHHDGQ 192

Human   177 QDHDTHHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLRS 241
            |:|||:||||||||..|.||||||:|.||||:||:|::|||||:||||.|...|..||.||||||
 Frog   193 QNHDTYHHHWREGNTSSSARCEVCKKNCGSSEVLSGMKCEWCGIQAHSACYIILTHECTFGRLRS 257

Human   242 LVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTLKIFDGD 306
            :||||.||.|....|||...|||.|..:..:..|..:.....|..:||..:.:|.||:|||:||.
 Frog   258 MVLPPNCVHLQARNFSKMHCFRISENIQAEQDEDNENDGIIQGSVKETPTSADSSKQSLKIYDGH 322

Human   307 DAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACD-------AWAGGK 364
            |||:|:|.|:::|.|:|.:|||:||||||::||::|...||..|...:...|       |...||
 Frog   323 DAVKRNQPRIISVPRIAKSEEVVEAALRAYYIPDEPQDYELQTLMQQTLVSDDIINRNGAMEDGK 387

Human   365 AGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPKSTARSVVLE 429
            .||..          .|||||||:|||.|:.:|:|||||||:||||||:|:.|..:.|.::|:.|
 Frog   388 VGSVF----------KEATPEAWMIRAKPKEREILKIYPGWMKVGVAYISIPVNKEHTVQTVIQE 442

Human   430 VLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQGGLELQISPRSSRGTDRG 494
            ||..||||.|:.|:|:||||.|..:.|||.:|..|:.:.|||.::|:..:......|
 Frog   443 VLIQLGRQKENLENFRLVEVLMSSKQVQRMVLPFEEIIFDRLNEVRKTSIRQMNQTR-------- 499

Human   495 CPQQGSLCGPF-------PRFPVDLIPGSVPDALFCCFAGEETEGLVRWCRSPRPSIPAPLPADV 552
                      |       |...:.:....:|..|    :.||...|::...:.:..:.:.:||
 Frog   500 ----------FYIEENEKPEIKIHIFISGLPPLL----SSEEYTDLLKEHLAIKDKLVSVIPA-- 548

Human   553 CAAATVVSVSHIYSSQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCP 617
                        ||.||||||::.||:||||::||:||.::..:.|..:::|.::|.|||.::||
 Frog   549 ------------YSPQGAVVLEILCFSEAERIFMLVKDTSINNKQLHGVIIPHIMHEKLPQETCP 601

Human   618 LLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWV 682
            ||||||||||||||||||.||||||||||||:|||||||||.|.||:||.|||||||||||||||
 Frog   602 LLVFVNPKSGGLKGRDLLYSFRKLLNPHQVFELTNGGPLPGFHTFSRVPYFRVLVCGGDGTVGWV 666

Human   683 LGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTIL 747
            ||||||.|::|||.|||:|:||||||||||||||||||||||||:|:|:||:||:.|||||||||
 Frog   667 LGALEEIRHKLACTEPSIAVLPLGTGNDLGRVLRWGAGYSGEDPYSILISVNEAENVLMDRWTIL 731

Human   748 LDAHEAGSA-ENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRV 811
            |||.||... ||..::.:|||||||:||||||||||||||||.|||.|||||.||.|||||||:.
 Frog   732 LDAQEAVDVMENGISEPDPPKIVQMNNYCGIGIDAELSLDFHHAREIEPGKFNSRFHNKGVYVKA 796

Human   812 GLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKPRMDDGLL 876
            ||||:||:|:||:.::|||::||||||:||||||:|||||||||||||||:|.|:.|||:|||||
 Frog   797 GLQKLSHNRNLHRDMKLQVDQQEVELPNIEGLIFLNIPSWGSGADLWGSDNDNRYGKPRIDDGLL 861

Human   877 EVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGHMIISAAGPKVHM 941
            ||||||||||||||||||||||||||||||||||||..|||||||||:|.||.:|||||||||||
 Frog   862 EVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKPIPVQVDGEPWIQPPGQIIISAAGPKVHM 926

Human   942 LRKAKQKPRR-AGTTRDARADA 962
            |:|:|||.:: :.:::|.:.|:
 Frog   927 LKKSKQKQKKTSASSKDTKGDS 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DGKQ	XP_047305643.1	C1_DGKtheta_typeV_rpt1	60..113	CDD:410353	41/52 (79%)
		C1_DGKtheta_typeV_rpt2	117..172	CDD:410354	39/55 (71%)
		C1_DGKtheta_typeV_rpt3	186..246	CDD:410404	41/59 (69%)
		RA1_DAGK-theta	297..394	CDD:340631	47/103 (46%)
		Ubl1_cv_Nsp3_N-like	397..479	CDD:475130	42/81 (52%)
		DAGKc	619..743	CDD:214487	105/123 (85%)
		DAGKa	770..922	CDD:214486	126/151 (83%)
dgkq	XP_002935917.1	C1_DGKtheta_typeV_rpt1	76..128	CDD:410353	41/51 (80%)
		C1_DGKtheta_typeV_rpt2	132..188	CDD:410354	39/55 (71%)
		C1_DGKtheta_typeV_rpt3	200..262	CDD:410404	43/61 (70%)
		RA1_DAGK-theta	313..407	CDD:340631	47/103 (46%)
		RA2_DAGK-theta	410..505	CDD:340481	44/112 (39%)
		DAGKc	603..727	CDD:214487	105/123 (85%)
		DAGK_acc	755..907	CDD:459866	126/151 (83%)