Protein Alignment DGKG and Dgkg

DIOPT Version :10

• Sequence 1: NP_001337.2
• Gene: DGKG / 1608
• HGNCID: 2853
• Length: 791
• Species: Homo sapiens
• Sequence 2: NP_037258.1
• Gene: Dgkg / 25666
• RGDID: 2499
• Length: 788
• Species: Rattus norvegicus
• Alignment Length: 791
• Identity: 698/791 - (88%)
• Similarity: 736/791 - (93%)
• Gaps: 3/791 - (0%)

Human     1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMRAYLEV 65
            |.:.:||.|:.|||||||||||||||||||.|.||||||||||||||:|||||||||||||||||
  Rat     1 MSDGQWVCLSSEEFDQLQKYSEYSSKKIKDVLAEFNEGGSLKQYDPHKPISYDVFKLFMRAYLEV 65

Human    66 DLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEACAPDTESNMAE 130
            ||||||||:||||||||||.||.|||.||||:||.|.:|:   ||::..|||.||||||||...:
  Rat    66 DLPQPLSTNLFLAFSQKPRQETPDHPKEGASSSEPNVSDS---NAESTAKADAACAPDTESKPIK 127

Human   131 KQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKLEFMFRLYDSDENGLL 195
            .|.|:|:..||.|...|...:|||::|:||||||||||||:|||||||||||||||||||||.||
  Rat   128 TQVPSEELEAAAPWGEPNAPASSSDAPIVYLKDVVCYLSLMETGRPQDKLEFMFRLYDSDENELL 192

Human   196 DQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFVSLQEWVHGGMTTIPLLVLLG 260
            ||||:|.||:||||:||||||||||||||||||||||||::||||||:|||.|||||||||||||
  Rat   193 DQAELDQIVSQMLHVAQYLEWDPTELRPILKEMLQGMDYNKDGFVSLEEWVSGGMTTIPLLVLLG 257

Human   261 MDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKTY 325
            ||||.||||||||||:||||||||||||||||||||||||||.||||.||:||||.:||||||||
  Rat   258 MDDSASKGDGRHAWTLKHFKKPTYCNFCHIMLMGVRKQGLCCIYCKYAVHQRCVSNSIPGCVKTY 322

Human   326 SKAKRSGEVMQHAWVEGNSSVKCDRCHKSIKCYQSVTARHCVWCRMTFHRKCELSTLCDGGELRD 390
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||:|
  Rat   323 SKAKRSGEVMQHAWVEGNSSVKCDRCHKSIKCYQSVTARHCVWCRMTFHRKCELSTACDGGELKD 387

Human   391 HILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKF 455
            ||||||||.|:||||...|||...:|||||||||||||:|||||||||||||||||||||||:||
  Rat   388 HILLPTSIYPVTRDRQAGKSDSGAAAKGELVMQYKIIPSPGTHPLLVLVNPKSGGRQGERILQKF 452

Human   456 HYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLG 520
            |||||||||||||.||||||||||:||||||||||||||||||||||||||||.|||||||||||
  Rat   453 HYLLNPKQVFNLDKGGPTPGLNFFQDTPDFRVLACGGDGTVGWILDCIDKANFTKHPPVAVLPLG 517

Human   521 TGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSI 585
            |||||||||||||||||||||||||:||||||||||||:|||:|||||||||||||:||||||||
  Rat   518 TGNDLARCLRWGGGYEGGSLTKILKEIEQSPLVMLDRWYLEVMPREEVENGDQVPYNIMNNYFSI 582

Human   586 GVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNI 650
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||
  Rat   583 GVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVEVDLSNI 647

Human   651 FLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAME 715
            ||||||||||||||||||||||.||||||||||||.||||||||.||||||||||||||||||||
  Rat   648 FLEGIAILNIPSMYGGTNLWGETKKNRAVIRESRKSVTDPKELKCCVQDLSDQLLEVVGLEGAME 712

Human   716 MGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF 780
            ||||||||||||||||||:||||||.|||||||||||||||.|.|||||||||||||||||||||
  Rat   713 MGQIYTGLKSAGRRLAQCSSVTIRTKKLLPMQVDGEPWMQPPCMIKITHKNQAPMMMGPPQKSSF 777

Human   781 FSLRRKSRSKD 791
            |||||||||||
  Rat   778 FSLRRKSRSKD 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DGKG	NP_001337.2	DAG_kinase_N	5..175	CDD:464196	123/169 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..103		15/20 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..154		17/36 (47%)
		EFh	179..248	CDD:238008	60/68 (88%)
		C1	255..328	CDD:412127	65/72 (90%)
		C1_DGKgamma_rpt2	337..395	CDD:410442	55/57 (96%)
		DAGKc	436..557	CDD:214487	115/120 (96%)
		DAGKa	578..752	CDD:214486	167/173 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..791		22/22 (100%)
Dgkg	NP_037258.1	DAG_kinase_N	5..172	CDD:464196	123/169 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..150		35/69 (51%)
		EFh	176..245	CDD:238008	60/68 (88%)
		C1	252..325	CDD:412127	65/72 (90%)
		C1_DGKgamma_rpt2	334..392	CDD:410442	55/57 (96%)
		DAGKc	433..554	CDD:214487	115/120 (96%)
		DAGKa	575..749	CDD:214486	167/173 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..788		19/19 (100%)