Protein Alignment SLC5A12 and CG2187

DIOPT Version :10

• Sequence 1: NP_848593.2
• Gene: SLC5A12 / 159963
• HGNCID: 28750
• Length: 618
• Species: Homo sapiens
• Sequence 2: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Alignment Length: 568
• Identity: 187/568 - (32%)
• Similarity: 307/568 - (54%)
• Gaps: 36/568 - (6%)

Human     6 FAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGT 70
            |.:.||.||..:...|:||||:|....:.|.|:.|:|.||::|...|:.:||.||.:|.:.::..
  Fly    24 FGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSI 88

Human    71 PSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQT 135
            |:|.|.:|.:::...:|.|.||.:...:.:||||.:.:::.||||::||||..|...|..::..:
  Fly    89 PAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNS 153

Human   136 ILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVL 200
            .|...|.::.|:||..||||.::.........:|.||..|||:|||||||..|..:|::..:.|.
  Fly   154 FLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVG 218

Human   201 IQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCIS 265
            :.|:..:||...|:|::::|.|.: |||.:||..|.|||..|:||.|.|.|..|:|||.:||.:|
  Fly   219 VLGTIRSGGMFTVMERASDGGRFN-FDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVS 282

Human   266 CKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATM 330
            ..:..|||.:|..:.||..||......||:||::.:..|||..:|::|.||::||:||.:|...:
  Fly   283 LPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHL 347

Human   331 PGLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISK-------GLCLLF 388
            .|:||:|::|.||..||::::::|:||.|.:.|::|....| ::..:.|..|       |.|:|.
  Fly   348 AGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRH-TEARANWAMKLIVVVMGGYCILG 411

Human   389 GVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFW-V 452
            |.|..:       ...::|..::|.|:..|.::|:|.||:..|..|.|.|:..::..:....| :
  Fly   412 GFMVQN-------FNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMVWII 469

Human   453 AIGAFIYPAPASKTWPLPLSTDQC------------IKSNVT------ATGPPVLSSRPGIAD-T 498
            |.|...:.:...|...||.|.|||            .|::.|      .:|.||.::.....| :
  Fly   470 ANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFS 534

Human   499 WYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLF 546
            .|.||:.:|..:|.....:..:.:|.|......|...|.|..|....|
  Fly   535 LYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKF 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A12	NP_848593.2	SLC5sbd_SMCT2	3..527	CDD:212089	182/547 (33%)
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	180/542 (33%)