Protein Alignment SLC5A12 and CG32669

DIOPT Version :10

• Sequence 1: NP_848593.2
• Gene: SLC5A12 / 159963
• HGNCID: 28750
• Length: 618
• Species: Homo sapiens
• Sequence 2: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 213/534 - (39%)
• Similarity: 317/534 - (59%)
• Gaps: 34/534 - (6%)

Human     9 WDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTPSE 73
            |||.:.|.:..||..||:::.....|::|:.|:|:..|.|:..||..||.||||||||:||...|
  Fly     7 WDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSME 71

Human    74 VYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILY 138
            .|::|..|:|..::|:....:.:.|.:|||||....|.||||:|||....|.||::.:.:|.:||
  Fly    72 NYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLY 136

Human   139 TGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQG 203
            .|:|||||||||..|||.....|:...|:|||||.||||:|||:.||.:|.::|.....:|:|..
  Fly   137 MGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICA 201

Human   204 STHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKT 268
            ...||....:...:....|:::.:|.|||..|||::|..:||..|:|.||||||:.:||.::.|:
  Fly   202 WVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKS 266

Human   269 EKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGL 333
            ...|:.||::.|..|.::.:...||||.:|.:::||||...|.:::.||:||.||::......||
  Fly   267 LSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGL 331

Human   334 PGLFVACAFSGTLSTVASSINALATVTFEDFVK---SCFPH--LSDKLSTWISKGLCLLFGVMCT 393
            .||||:..|..:|||::|.|::||.||.||::|   ||...  |:|:.:.|.||.|.|.||.:|.
  Fly   332 AGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCI 396

Human   394 SMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFI 458
            .||..|..:||::||:|||.|:.|||:||||:||:.....|.|||:||||..:...||:..|
  Fly   397 GMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFG--- 458

Human   459 YPAPASKTWPLPLSTDQCIKSNVTATGPPV---------LSSRPGIADT-----WYSISYLYYSA 509
            .|.|       ||     :..:::..|.||         |.:...:|:.     .|.|||::|:|
  Fly   459 QPKP-------PL-----VSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAA 511

Human   510 VGCLGCIVAGVIIS 523
            :|.|.....|.::|
  Fly   512 LGFLITFFGGWLLS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A12	NP_848593.2	SLC5sbd_SMCT2	3..527	CDD:212089	213/534 (40%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	213/534 (40%)