Protein Alignment CYP26A1 and Cyp312a1

DIOPT Version :9

• Sequence 1: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Sequence 2: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 114/534 - (21%)
• Similarity: 200/534 - (37%)
• Gaps: 145/534 - (27%)

Human    14 FVLPLLLFLAAIKLWDLYCVSGRDRSCAL----PLPPGTMGFPFFGETLQMVLQRRKFLQMKRRK 74
            |.|...|.|.|:.|:.||....:.|...|    |.||   ..||.|.
  Fly     2 FWLGFGLLLLALSLYLLYVFERQSRIDRLTHKWPAPP---ALPFIGH------------------ 45

Human    75 YGFIYKTHLFGRPTVRVMGADNVRRI--LLGEHRLVSVH------W-----------PASVRTIL 120
                  .|:.    .:::|...:||.  ::.||    :|      |           |..::.:.
  Fly    46 ------LHIL----AKLVGPHPLRRATEMINEH----LHDHRAKLWMGTKLYLVDCNPKDIQALC 96

Human   121 GSGCL--------------------SNLHDSSHKQRKKVIMRAFSREALECYVPVITE------- 158
            .:..|                    |.....||  |:|::|.||:...::.:|.|..:
  Fly    97 SAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSH--RRKIVMPAFNYTMIKQFVAVFEKQSRILLT 159

Human   159 ------EVGSSLE--QWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDG-DSEQQLVEAF 214
                  |.|..::  |.:||.....:.         ..|:.:.:|.:.....:. |:.:.::...
  Fly   160 NVAKFAESGDQIDFLQLISCFTLDTIC---------ETALGVSVGSQSSAKSEYLDAVKSILVII 215

Human   215 EEMTRNLFSLPIDVPFSGLYR-GMKARNLIHARIEQNIRAKICGL-------RASEAGQGCK--- 268
            ::..:|:|           || ....:...|.:.||.:...:.|.       |..|..|..:
  Fly   216 DKRLKNIF-----------YRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRN 269

Human   269 ----DA-----------LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGL 318
                ||           |..|:......|:.|.::.:::....::|||.:.||:.....:..:.|
  Fly   270 YQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTL 334

Human   319 YPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL 383
            :|...|:.|||:.|   :|..::...:.:|.:.||:::...||||||:.|..|...|.|.....:
  Fly   335 HPEHQQRCREEVWS---VCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTI 396

Human   384 NGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 448
            |.:.||||.:||.|........:.|.:...|.|||:.:.........:||||..|.|||:|:.:|
  Fly   397 NDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYA 461

Human   449 KILLKIFTVELARH 462
            .::||:....|.|:
  Fly   462 MVMLKMVLAHLLRN 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	114/534 (21%)
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	104/501 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910