Protein Alignment CYP26A1 and Cyp9c1

DIOPT Version :9

• Sequence 1: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Sequence 2: NP_523850.1
• Gene: Cyp9c1 / 37941
• FlyBaseID: FBgn0015040
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 114/548 - (20%)
• Similarity: 199/548 - (36%)
• Gaps: 135/548 - (24%)

Human    18 LLLFLAAIKL----WDLYC---VSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRK--------- 66
            |.:|:|.|.|    |.:|.   .|.|..:...|:       |..|.....||..::
  Fly     6 LSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPI-------PLLGNIPWSVLMGKESYIKHSIDL 63

Human    67 FLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVR----TILGSGCLSN 127
            .|::|:.|   :|.......|...:...:.:|::.:......:.|......    |.:.|..|.:
  Fly    64 HLRLKQHK---VYGVFNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLS 125

Human   128 LHDSSHKQRKKVIMRAFS----REALE----CYVPVITEEVGSSLEQWLSCGERGLLVYPEVKRL 184
            |.|...||.:..:...|:    |:..|    |.|     |....:::.|..|...|    |:|..
  Fly   126 LRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNV-----EAVDFVQRQLDAGTSEL----ELKDF 181

Human   185 MFRIAMRIL----LGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKAR-NLIH 244
            ..|....::    .|.:             |.:|::.....||:...:.....:.|:|.. .::.
  Fly   182 FTRYTNDVIATAAFGIQ-------------VNSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILM 233

Human   245 ARIEQNIRAKICGLR---------------ASEAGQGCKDALQLLIEHSWERGERLDMQALKQSS 294
            .::.:.:|..:..:.               ..|......|.:.||:|.  :|..:.:.:...:|:
  Fly   234 PKLMKALRVPVMDMNNVDYFKKLVFGAMKYRKEQSIVRPDMIHLLMEA--QRQFKAEQEGSAESA 296

Human   295 TE---------------LLF--GGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 342
            .:               |||  .|.||.|:..:.....|.:.|.|.:|:..|:    |..|....
  Fly   297 AQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEI----LAVKEQLG 357

Human   343 NK-LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVI---------YS 397
            .| ||.:.|..:||:.||:.|:||..||.....|:....|:|..   .:|..|:         .:
  Fly   358 EKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKD---EEGEVVVNLREDDLVHIN 419

Human   398 ICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLK--IFTVELA 460
            :...|...:.|...|:|.|:||...|..:..:|:::|||.|.|||:|...|.:.:|  ||.:.|.
  Fly   420 VGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLR 484

Human   461 RHCDWQLLNGPPTMKTSPTVYPVDNLPA 488
            .|                 :.|.|..||
  Fly   485 YH-----------------LKPTDRTPA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	114/548 (21%)
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	105/517 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030