Protein Alignment CYP26A1 and Cyp4ac3

DIOPT Version :9

• Sequence 1: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Sequence 2: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 86/374 - (22%)
• Similarity: 165/374 - (44%)
• Gaps: 49/374 - (13%)

Human   116 VRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPE 180
            :|..||.|.|.::....| .|:|.:..||....|:.::.:..||    .::::...::.:....|
  Fly   123 IRPFLGDGLLISIDQKWH-TRRKTLTPAFHFNILQSFLSIFKEE----SKKFIKILDKNVGFELE 182

Human   181 VKRLMFRIAMRILLGCEPQLA------GDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLY----- 234
            :.:::.:..:..:  ||..|.      .:|:..::.:..||.:.......|:  .|...|
  Fly   183 LNQIIPQFTLNNI--CETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPL--MFFNWYFFLFG 243

Human   235 ---RGMKARNLIHA-------RIEQNIRAKICGLRASEAGQGCKDA-LQLLIEHSWERGERLDMQ 288
               :..:....||.       |..|..:.|..| :..|.|:..:.| |..|:  :.|...::|.|
  Fly   244 DYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLG-QVDEFGKKQRYAMLDTLL--AAEAEGKIDHQ 305

Human   289 ALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD-----NKLDME 348
            .:.......:|||::||:::....:..|.|:..|.::..|||          ||     :::.|.
  Fly   306 GICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEEL----------QDLPEDIDEVSMF 360

Human   349 ILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 413
            ...:|.::.|||||:|||.|..|...|..::...:||..:||...:...|.|....|..|....:
  Fly   361 QFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQ 425

Human   414 FNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
            |.|:||:..:..:...|:|:||..|.|:|:|::|..:.:|:....:.|:
  Fly   426 FLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRN 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	86/374 (23%)
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	86/374 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910