DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC15 and CG5196

DIOPT Version :9

Sequence 1:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens
Sequence 2:	NP_650191.1	Gene:	CG5196 / 41522	FlyBaseID:	FBgn0038039	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	78/327 - (23%)
Similarity:	124/327 - (37%)	Gaps:	108/327 - (33%)

- Green bases have known domain annotations that are detailed below.

Human    17 RRVLSWVPVL---VIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFF----TWTYWK 74
            ||.|.|.|:.   :|..:.|.:.|       :.::..|..|......:.|:|:..    |:.|..
  Fly     9 RRFLHWGPITALSIIKCITLTTLY-------MNSMWWPPNKSFAGFAHQALFLLLSTLATFNYVM 66

Human    75 SIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKP 139
            :..|.|....:::|              |:..|.                :..:::|.:|...|.
  Fly    67 ATLTGPGLMPKQWH--------------PKDPKD----------------AQFLQYCKKCEGYKA 101

Human   140 DRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRG-- 202
            .|.|||..|..||.||||||||:|:|:|::|:.:|..||.:|:|..|. .|.|..  ..:|||
  Fly   102 PRSHHCRKCDRCVKKMDHHCPWINHCVGWANHAYFTYFLLFSILGSLQ-GTVVLC--CSFWRGIY 163

Human   203 ----------ELPSVRSKFHVLFLLFVACMFFVSLVI---------LF-----------GYHCWL 237
                      .|.||:    ...|..:.|:..:.|.|         ||           |...|:
  Fly   164 RYYYLTHGLAHLASVQ----FTLLSIIMCILGMGLAIGVVIGLSMLLFIQLKTIVNNQTGIEIWI 224

Human   238 VS-------RNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDKKKFWLIPIGSSPGDGHSF 295
            |.       ||....:.|..|          ::||:..|::.||.|:.:        ..|||..:
  Fly   225 VEKAIYRRYRNADCDDEFLYP----------YDLGWRANLRLVFNDECQ--------KRGDGIEW 271

Human   296 PM 297
            |:
  Fly   272 PV 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	59/211 (28%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
CG5196	NP_650191.1	zf-DHHC	89..223	CDD:279823	43/140 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820