DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC15 and CG4483

DIOPT Version :9

Sequence 1:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens
Sequence 2:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	79/323 - (24%)
Similarity:	133/323 - (41%)	Gaps:	103/323 - (31%)

- Green bases have known domain annotations that are detailed below.

Human    17 RRVLSWVPV--LVIVLVVLWSYYAYVFELCLVTVL-------SPAEKVIYLILYHAIFV--FFT- 69
            ||.:.|.|:  |.:.|:|.|            ||:       :|...:..::.|..|::  |.|
  Fly    10 RRFIHWGPITLLTLTLIVTW------------TVIHMNSMWWAPGSSLESVLNYALIWIQTFGTL 62

Human    70 WTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRC 134
            :.:.:|:...|.....|:|              |::.|..:.                ::||.||
  Fly    63 YNFIRSLMVGPGFVPLKWH--------------PQLTKDKMF----------------LQFCTRC 97

Human   135 HLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAY----SVLYCLYIATTVF-- 193
            :..|..|.|||..|..||:||||||||:|.|:|:||...|:.||.:    |:...:.|.:.|.
  Fly    98 NGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRG 162

Human   194 ---SYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVI--------LFGYHCWLVSRNKTTLE- 246
               .:.|:|....:.:|    |:.....:||:|.:.:::        |.......:.:|:|.:|
  Fly   163 IKKRWLIRYGLRHMATV----HLTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILKNQTEIEN 223

Human   247 ------AFCTPVFTSGPEKN------GFNLGFIKNIQQVFGDKKKFWLIPIGSSPGDGHSFPM 297
                  ||....:   |.|.      .:|||:..|:::||            .|.|||.|:|:
  Fly   224 WIVKKAAFRRNAY---PRKGIKPFVYPYNLGWKTNMREVF------------FSTGDGISWPV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	58/202 (29%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	42/155 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820