DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZDHHC15 and CG10344

DIOPT Version :9

Sequence 1:NP_659406.1 Gene:ZDHHC15 / 158866 HGNCID:20342 Length:337 Species:Homo sapiens
Sequence 2:NP_611671.1 Gene:CG10344 / 37565 FlyBaseID:FBgn0034729 Length:278 Species:Drosophila melanogaster


Alignment Length:299 Identity:71/299 - (23%)
Similarity:127/299 - (42%) Gaps:71/299 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    23 VPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFF-TWTYWKSIFTLPQQPNQK 86
            |.:|..:::.::....::||:           |:.|..:|....|| |:|:..::|.:       
  Fly    13 VDILCFLIIAVFLPVVFMFEI-----------VVVLPAFHEPGGFFHTFTFLMAMFLV------- 59

Human    87 FHLSYTDKERYENEERPEVQKQMLVDMA---KKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVC 148
            |::            :..:...|::|.:   ||  |...:.....|.|..|..:.|.|..||..|
  Fly    60 FNI------------KGNMIACMMIDTSVNVKK--VEPPSDQLNWRECGECQKLAPPRSWHCKAC 110

Human   149 AMCVLKMDHHCPWVNNCIGFSNYKFFLQF-----------LAYSVLYCLYIATTVFSYFIKYWRG 202
            .:|:||.||||.:...|||..|::||:.|           |.|:.:|...|...::|.::...:.
  Fly   111 KVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKL 175

Human   203 ELPSVRSKFHVLFLLFVACMF--FVSL--------VILFGYHCWLVSRNKTTLEAFCTPVFTSGP 257
            ..|.:    |::...|...|:  |.||        |:|..||..:|.|...:.:       .:..
  Fly   176 ACPML----HLVTGSFWTNMYLVFYSLNILALAYGVLLLAYHVPIVLRGGVSAD-------RTKE 229

Human   258 EKNGFNLGFIKNIQQVFGDKKKF-WLIPIGSS--PGDGH 293
            .|..::.|..:|::.|||::... ||.|:..|  |.||:
  Fly   230 SKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDLPEDGY 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZDHHC15NP_659406.1 zf-DHHC <126..308 CDD:327686 53/192 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 306..337
CG10344NP_611671.1 zf-DHHC 93..220 CDD:279823 38/130 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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