DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC15 and CG17075

DIOPT Version :9

Sequence 1:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens
Sequence 2:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	57/202 - (28%)
Similarity:	83/202 - (41%)	Gaps:	55/202 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    18 RVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHA-----IFVFFTWTYWKSIF 77
            ::..|   ||::|..:.||:          ||.||        :||     ::...|..|...|.
  Fly   114 QIFGW---LVLLLFGVASYW----------VLIPA--------FHARIQGPLYGLITGLYLVHIA 157

Human    78 TLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHL----IK 138
            :         ||:....:..:.|.|...:...:|      |.:.|:....|....||||    ..
  Fly   158 S---------HLTALLTDPADKELRRVHRNDRIV------PEFDRSKHSHVIENGRCHLCNIRTS 207

Human   139 PDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFS----YFIK- 198
            .:|..|||||..||.|.||||.|:|:|||..||..||..:..:|:..|.|...|.:    |:|:
  Fly   208 SNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQP 272

Human   199 -----YW 200
                 ||
  Fly   273 DWLSFYW 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	35/89 (39%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	33/81 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810