Protein Alignment AWAT1 and Dgat2

DIOPT Version :10

• Sequence 1: NP_001013597.1
• Gene: AWAT1 / 158833
• HGNCID: 23252
• Length: 328
• Species: Homo sapiens
• Sequence 2: NP_610318.1
• Gene: Dgat2 / 35719
• FlyBaseID: FBgn0033215
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 115/322 - (35%)
• Similarity: 176/322 - (54%)
• Gaps: 19/322 - (5%)

Human    10 FQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWV--RNW 72
            |.|::|:...:|:|.:...|  ::..||..||.   |.|.|::|:..|..:.....:.|:  |..
  Fly    24 FTSMLLILLSVSFLLVAGSL--IYGGLLVRSLM---VTYLAYVFVHHKKTQSVVDGNGWMITRTN 83

Human    73 CVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATL 137
            .:..|.|||||:.::||.:|....||::...|||:|..|...|...|.:.:.:.||.:.|.|.||
  Fly    84 LLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLEISKWLELFPQVRPKLGTL 148

Human   138 SWFFKIPFVREYLMAKGVCSVSQPAINYLLSHG------------TGNLVGIVVGGVGEALQSVP 190
            ...|.:||:||.|...|:.|||:.|:..:||..            |.|.|.|:|||..||:.|.|
  Fly   149 DQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTSNAVAILVGGAQEAMDSHP 213

Human   191 NTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVF 255
            ....|.|:.||||||.|::.|:.:||:|:|||.:::|||....:|.:.:||...:::.|....:.
  Fly   214 GQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLLRRFQDFVKKLTGVSPLIP 278

Human   256 YGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALHKLFDQHKTHY 317
            .|:.|...:.|.||:.|.||.|||.|:.:.:.|.|..|.|||.|...:::|.|||||:|..|
  Fly   279 VGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVDKVHGQVIESLEKLFDQYKDKY 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AWAT1	NP_001013597.1	LPLAT	35..327	CDD:473073	109/297 (37%)
Dgat2	NP_610318.1	LPLAT	74..340	CDD:473073	99/265 (37%)