Protein Alignment MOSPD2 and csr101

DIOPT Version :10

• Sequence 1: NP_689794.1
• Gene: MOSPD2 / 158747
• HGNCID: 28381
• Length: 518
• Species: Homo sapiens
• Sequence 2: NP_594057.1
• Gene: csr101 / 2542218
• PomBaseID: SPAC589.09
• Length: 388
• Species: Schizosaccharomyces pombe
• Alignment Length: 281
• Identity: 65/281 - (23%)
• Similarity: 120/281 - (42%)
• Gaps: 68/281 - (24%)

Human    12 LISETRRRFE--AEYVTD-----KSDKYDARDVERLQQDDNWVESYLSWRHNIVDETLKMLDESF 69
            :|.:|..||:  .||...     |.|..||..|.           :|:..:|...|..:.|..:.
pombe    52 MIQKTWPRFQEHKEYRESFIRLAKCDSPDAILVR-----------FLASCNNDSHEASQKLINTL 105

Human    70 QWRKEISVNDL--------NESSIPRWL--LEIGVIYLHGYDKEGNKLFWIRVKYH--------- 115
            |||.:..|..:        .|::..::|  |..|.:.:.|.|.....:.:|:|..|
pombe   106 QWRVDTGVERIVERGELYAKETNDDQFLEQLRTGKVTMLGRDLSDRPICYIQVHLHQPSKLTQNS 170

Human   116 ---------------VKDQKTILDKKKLIAFWLERYAKRENGKPVTVMFDLSETGINSIDMDFVR 165
                           ::.|||:.|             ..::.:.|.|:||||...::::|..||:
pombe   171 LREMTVWVMETMRLFLRPQKTLKD-------------SMDSPQNVNVLFDLSNFSLHNMDYSFVK 222

Human   166 FIINCFKVYYPKYLSKIVIFDMPWLMNAAFKIVKTWLGPEAVSLLKFT-SKNEVQDYVSVEYLPP 229
            ::.:|.:.|||:.|...::...||:..:.:.|:|.|:.||..:.:.|| |.|:::.|:....:|.
pombe   223 YLASCLEYYYPQSLGVCILHKSPWIFRSVWNIIKGWIKPEIAAKIVFTQSANDLEKYIDYSVIPT 287

Human   230 HMGGTDP--FKYSYPPLVDDD 248
            .:||.:.  |:|..|...::|
pombe   288 SLGGGNKKIFQYIEPVEHEND 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MOSPD2	NP_689794.1	SEC14	93..234	CDD:469559	38/165 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..308
		Motile_Sperm	327..431	CDD:459882
		Required for FFAT motif binding and phosphorylated FFAT motif binding. /evidence=ECO:0000269|PubMed:33124732, ECO:0007744|PDB:6TQS, ECO:0007744|PDB:6TQU	365..366
csr101	NP_594057.1	CRAL_TRIO	138..291	CDD:459890	37/165 (22%)