Protein Alignment FAAH2 and CG5112

DIOPT Version :10

• Sequence 1: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_651400.1
• Gene: CG5112 / 43083
• FlyBaseID: FBgn0039341
• Length: 523
• Species: Drosophila melanogaster
• Alignment Length: 526
• Identity: 210/526 - (39%)
• Similarity: 312/526 - (59%)
• Gaps: 23/526 - (4%)

Human     7 ARIQLFLLRALGFLIG-LVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDV 70
            |.:.:...|.|.|::. .:|....|.|.|....:|  .:|:     |.::||:.||:|:.:..|:
  Fly    13 ALVHILSDRLLEFVLDWYLGEHKRVSGPPSLEQQT--TITK-----SAVELAQQIRERRQRSYDI 70

Human    71 VQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQ 135
            |:||..||:.||..:|.:|...|.||:.:|..:|:||.||:..:..| .:.||||||.:.|::..
  Fly    71 VKAYCERIESVNRDLNAVVDGPFPEALDQAREIDRKLDEKEYSDEDL-RRLPFLGVPFSTKDSTA 134

Human   136 LQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQ 200
            :.|..::.||:.|:...:.|||..|.|:|.:|||.:..:|..|:..|.||.|.:.|.:||||||:
  Fly   135 VAGRLHTLGLLARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLR 199

Human   201 HIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQ-E 264
            ..||||||||...:||.|:..|:|:|||||||:|||..|||||||:.|.| |........|.: :
  Fly   200 RSVGGSSGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAV-NMAGCTFRTGKEKD 263

Human   265 LFLCTGPMCRYAEDLAPMLKVMAGPGIK-RLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIM 328
            ..:|.|||.|.|.||.||::|:..|.:| :||||.||.||.|:::::..:|.: ..:.::::...
  Fly   264 TMVCAGPMSRSARDLLPMMQVLVEPSLKAKLKLDQKVDLKRLRYFYVSSNGMA-QCNPINRETER 327

Human   329 TQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWE 393
            ...|:..|.|.:.|..|:|..|...|.:.::|...|:      :||..|..||| :|..::|..|
  Fly   328 VMYKIRKHFEAVSGKDVRHADLPYTKLTGKMWRYWMT------QEPANFNLLLG-NGAELNPFVE 385

Human   394 LIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVA 458
            |.|..||.|.|::.:| ..|::..|  ..||.:..:......:|.:.|:||||||..:.|.|..|
  Fly   386 LFKKILGQSDYSMAAI-YGLIDSVL--PKEKEKLMREATAKCKKSVQDLLGDDGVLFFHSSPRTA 447

Human   459 PKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTF 523
            |.|:.||.:..:|||..:|:.|.||.||.|:||::||:||||||||.|.||.|.||||:.||:||
  Fly   448 PFHYYPLVKFNDFAYFSLFNVLHLPATQVPMGLDSKGMPLGIQVVANPNNDRLCLAVAEELERTF 512

Human   524 GGWVCP 529
            ||||.|
  Fly   513 GGWVPP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	195/480 (41%)
CG5112	NP_651400.1	GatA	50..520	CDD:439924	201/487 (41%)