Protein Alignment FAAH2 and CG5191

DIOPT Version :10

• Sequence 1: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_650893.2
• Gene: CG5191 / 42431
• FlyBaseID: FBgn0038803
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 208/556 - (37%)
• Similarity: 319/556 - (57%)
• Gaps: 47/556 - (8%)

Human     1 MAPSFTARIQLFL----LRALGFLIGLVGRAALVL-----------GGPKFASKTPRPVTEPLLL 50
            |..|....|:|.|    ||.||:::....|:|:::           ...|...:...|:...||.
  Fly     1 MLKSIVTVIRLHLEELWLRILGYIMRRFLRSAMIVFSWFVVPYSRYTNIKVIRRKLPPIRSHLLE 65

Human    51 LSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEA 115
            :..:.||||||.||:|..:||:|||.|.:.|||:||.||:.|||||::||..:|..:|.......
  Fly    66 IPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREIDNVIAMGINSVE 130

Human   116 TLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC 180
            ::|...|.||:|:||||:..::||.|.:|.:.:...|||:||.||..:|.:|.|.|.::|..|||
  Fly   131 SMEELTPLLGIPVTVKESIAVKGMTNQAGRVFKTPQIAKSDAPVVEQIKRSGGIILLVSNTPELC 195

Human   181 MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKP 245
            :.:|:.|.:.|::.|||||:...|||||||...||:..|::|:.||||||.|:||.|:||:||||
  Fly   196 LLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWGHKP 260

Human   246 SPGVVPNKGQFPLAVGAQEL-----FLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDL 305
            :|..|..||..|    ..:.     |....||.|||:||..:||.|:.|...:|.||..:.:..:
  Fly   261 TPYAVSFKGHHP----TSDFPKWGDFFTIAPMTRYAKDLPLLLKCMSDPTGPKLTLDRPISVNGI 321

Human   306 KFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWI-AMMSAKG- 368
            :|::|::||.|.:|..:.:||.....:|....      :.:.|.::|||:|..:.: ||::.|.
  Fly   322 RFFFMDNDGPSGMMRPLSRDLHAAINRVATDF------NAKRVNIRKMKWSLDISLSAMLTMKNI 380

Human   369 ----HDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLR-YSNEKYQKF 428
                |..:|        |:..|.|..  |.:|:..|.|...:||:....|:..:: ..|.:::..
  Fly   381 ETIYHKTEE--------GEQPKTVCK--ETVKYFFGCSDSILPSVIFGHLQNFMKIIPNSRHKHL 435

Human   429 KAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNA 493
            .::.|:|:.|..:|||:|||||||:.|..|.:|:....:.....|..:|:.||||||.|.:||:.
  Fly   436 ASIIEALKTEFKEMLGNDGVFLYPTFPNTAHQHYQIYHKLLEPMYMAIFNTLGLPVTNCMIGLDR 500

Human   494 KGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCP 529
            :.||:||||||.|..|||:||||:.:|:.:||||.|
  Fly   501 RNLPMGIQVVANPGQDHLSLAVAREMERRYGGWVRP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	190/490 (39%)
CG5191	NP_650893.2	GatA	61..537	CDD:439924	195/496 (39%)