DRSC/TRiP Functional Genomics Resources

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Protein Alignment FAAH2 and GatA

DIOPT Version :10

Sequence 1:NP_777572.2 Gene:FAAH2 / 158584 HGNCID:26440 Length:532 Species:Homo sapiens
Sequence 2:NP_650775.2 Gene:GatA / 42283 FlyBaseID:FBgn0260779 Length:508 Species:Drosophila melanogaster


Alignment Length:498 Identity:139/498 - (27%)
Similarity:212/498 - (42%) Gaps:109/498 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    85 INGIVKYRFEEAMKEAHAVDQ--KLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMN 147
            :|..|:...|:|.::|...:|  ||.:...|   |:      ||.:.:|:.|..:.:..:.....
  Fly    40 LNAFVRLTPEQAGQQAQDAEQRYKLRQPISD---LD------GVTIAIKDNFCTKDVHTTCASRM 95

Human   148 RRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPY------DLQHIVGGS 206
            .:|.:...||||.:.||.|||:.||.||..:..|...:.:.:||.:.|.:      |...|.|||
  Fly    96 LQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRIAGGS 160

Human   207 SGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGP 271
            |||....:||......:|||.|||.|.||.:.|:.|.||:.|:|...|..|| |.:.::   .|.
  Fly   161 SGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPL-VNSMDV---PGI 221

Human   272 MCRYAEDLAPMLKVMAGPGIKRLKLD--------TKVHLKDLKFYWMEHDGGSFLMSKV------ 322
            ..|...|...:|..:|||.    |||        |::||.::         |...:|.|      
  Fly   222 FARSVSDCVAVLNTVAGPD----KLDSTTIRQPFTRLHLPEV---------GQIDLSTVRIGIPK 273

Human   323 -------DQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSF-------QLWIAMMSAKGHDGKE 373
                   ..:::.|..||...|| ..||||:.|.|.....|.       |..:|...|: :||  
  Fly   274 EYHCHGLSAEVLETWSKVADLLE-CSGASVRQVSLPNTAASIFVYTILNQCEVASNMAR-YDG-- 334

Human   374 PVKFVDLLGDHGKHVSPLWELIKWCLGLS--VYTIPSIGLALL---------EEKLRYSNEKYQK 427
             :::.....|. :....|:.|.: ..|.:  |.|....|..||         |:.||......:.
  Fly   335 -IEYGHRATDE-RSTEQLYALSR-AEGFNDVVKTRILTGNFLLLKKNYDHYFEKALRVRRLIAED 396

Human   428 FKAV-EESLRKELVDMLGDDGVFLYPSHPTVAP--KHHVPL------------TRPFNFAYTGVF 477
            |..| :.|.::|.||:|      |.|:..|.||  |....|            |:|.|.|     
  Fly   397 FARVFDSSAKEERVDIL------LTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMA----- 450

Human   478 SALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLE 520
               |:|....|:.|:..||||.:|:::...|:.|.|.||:::|
  Fly   451 ---GIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIE 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FAAH2NP_777572.2 GatA 45..524 CDD:439924 139/498 (28%)
GatANP_650775.2 GatA 1..491 CDD:439924 139/498 (28%)

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