Protein Alignment FAAH2 and CG7900

DIOPT Version :10

• Sequence 1: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_001097707.1
• Gene: CG7900 / 40957
• FlyBaseID: FBgn0037548
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 198/542 - (36%)
• Similarity: 300/542 - (55%)
• Gaps: 38/542 - (7%)

Human     8 RIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQ 72
            |:.:.|::.:..::..:..|.:.  .||.......|:...||.||..:|.:.::.|::..:::|:
  Fly     6 RLIVILVKVIALIVSPLLEAFVY--RPKSKRTLIPPIRSRLLTLSVQELRRRLQSRQLTSVELVR 68

Human    73 AYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQ---EDEATLENKWPFLGVPLTVKEAF 134
            .||.||:.||..:|.:::.||..|::||...|..:|..|   |.|...|.: |.||:|:|:||:.
  Fly    69 TYIERIEAVNKHLNALIESRFTAALEEATETDDLIASCQTAAEVEKLFEER-PLLGLPVTIKESC 132

Human   135 QLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDL 199
            .|:||..:.|.::|::..|:.|...|..||.||||||.::...|.|...|:...:.||..||||.
  Fly   133 ALEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCLNPYDS 197

Human   200 QHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLA----V 260
            :...||||||||....|..|:.|:|||||||||:|:.:.||||||||.|||..||.||.:    :
  Fly   198 ERTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFPNSLDPNI 262

Human   261 GAQELFLCTGPMCRYAEDLAPMLKVMAG-PGIKRLKLDTKVHLKDLKF-YWMEHDG-GSFLMSKV 322
            |.   :|..||:.|:||||:.:|:|||| ....:|:|:..|.|..:|. |.:..:| ..::...|
  Fly   263 GH---YLVEGPITRFAEDLSELLQVMAGKENSSKLRLNEPVQLNQIKVQYALAFEGINGWMHMAV 324

Human   323 DQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDH--- 384
            |:|:.....|...||:| ||.:|:.|||..::.|.:     |:..|..|::.:.:  ||.|.
  Fly   325 DKDITGAICKATTHLKT-LGLNVKKVKLPNLENSVE-----MALSGIAGQDLMDY--LLTDENPE 381

Human   385 --GKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLR-----YSNEKYQKFKAVEESLRKELVDM 442
              ||....:||::|...|.|.||..    ||:.|.:|     .|..|..::......|..|..::
  Fly   382 GSGKVRETVWEIVKSVRGHSKYTTN----ALIFELMRRTGAFMSQSKINQYMKETRELIGEFENL 442

Human   443 LGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPF 507
            |||:||.|:|:....||:|...:...:...||.:|:.||||||..|:|||.:|||:|:.|:..|.
  Fly   443 LGDNGVLLFPTLNLPAPRHKWSILSLWGVDYTLMFNVLGLPVTHVPMGLNERGLPIGLSVIGAPN 507

Human   508 NDHLTLAVAQYLEKTFGGWVCP 529
            .|.|.|.||..||:.||||..|
  Fly   508 QDRLCLRVAVELERAFGGWKPP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	187/498 (38%)
CG7900	NP_001097707.1	GatA	42..531	CDD:439924	192/504 (38%)