Protein Alignment FAAH2 and CG8839

DIOPT Version :10

• Sequence 1: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_610764.1
• Gene: CG8839 / 36340
• FlyBaseID: FBgn0033717
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 235/522 - (45%)
• Similarity: 328/522 - (62%)
• Gaps: 19/522 - (3%)

Human    18 GFLIGLVGRAAL-----VLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINR 77
            |::.|:: :|.:     ::.|.|  .::..|:|:.:||.|...||:.||::::..:.|::::|.|
  Fly    13 GYIFGIL-QACIRFVFRLIYGQK--GESVPPITDAILLESATSLARKIRKQELSSVQVLESFIRR 74

Human    78 IKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNS 142
            ||:|||::|.:|..|:::|:|||...|..:...|.....||.:.||||||:|.|:...::||.::
  Fly    75 IKEVNPILNCVVDERYDQALKEAAEADALIKSGQYSTEELEKEKPFLGVPITTKDCISVKGMLHT 139

Human   143 SGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSS 207
            :||..|||..|..||..:||::.|||||:.:||.||:|||:||:|.::||:.|.||...||||||
  Fly   140 AGLFERRDVRAARDADAMALMRKAGAIPIALTNVSEVCMWWESNNTVHGRTRNAYDTNRIVGGSS 204

Human   208 GGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGA-QELFLCTGP 271
            |||||..:||.|..|:|||||||||||||||||||||||..||.|.||||....| |..||..||
  Fly   205 GGEGCIQSAAASAFGLGSDIGGSIRMPAFFNGIFGHKPSKLVVSNVGQFPAPFSAEQNSFLGLGP 269

Human   272 MCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVH 336
            |.|:||||.||||:|||.....|.||..|.|..:||::.|.|||..|:|.||.||.....:|..|
  Fly   270 MSRFAEDLRPMLKIMAGEKAALLNLDEDVDLTKMKFFYQESDGGGRLVSAVDPDLREAMNRVAQH 334

Human   337 LETILG-ASVQHVKLKKMKYSFQLWIA-MMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCL 399
            |....| ..|:.::|...:.|..:|.| |....||.      |...||:....::...||.||..
  Fly   335 LREKFGNQKVERIQLPHFRQSAAIWFANMRDDSGHG------FAYQLGNLNHDINTYLELFKWFF 393

Human   400 GLSVYTIPSIGLALLEE-KLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHV 463
            |.|.:|...:..|:::. :.::.:.||.........||:||..:|||:||.:||:||||||.|:.
  Fly   394 GASKHTFIGLSTAIMDSAQCKHGSPKYDHLVRKRNELREELQSLLGDNGVLIYPTHPTVAPYHNE 458

Human   464 PLTRPFNFAYTGVFSALGLPVTQCPLG-LNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWV 527
            |:|||.||||||:.:.||.|.|..||| |.::|||||:|::|....|.|.||||:.||:.||||.
  Fly   459 PITRPINFAYTGIVNVLGFPATAVPLGKLGSEGLPLGVQIIANFNQDRLCLAVAEELERAFGGWA 523

Human   528 CP 529
            .|
  Fly   524 KP 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	224/483 (46%)
CG8839	NP_610764.1	GatA	49..525	CDD:439924	225/481 (47%)