Protein Alignment CYP11B1 and Cyp12d1-d

DIOPT Version :9

• Sequence 1: NP_000488.3
• Gene: CYP11B1 / 1584
• HGNCID: 2591
• Length: 503
• Species: Homo sapiens
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 110/441 - (24%)
• Similarity: 192/441 - (43%)
• Gaps: 68/441 - (15%)

Human    95 EDVEKLQQVDSLHPHRMSLEPWVAYRQH-----RGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAV 154
            :|:|.:.:.:.:.|.|..|:..|.:|:|     .|...|:.......|...|..:||..:.|..:
  Fly   101 KDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGL 165

Human   155 QRFLPMVDAVARDFSQALKKKVLQNARGSLTLDV----QPSIFHYTIEASNLALFGERLGLV-GH 214
            :.:...:..:..:|.:.:|:     .|...||:|    ...|.....|:..|..|..::||: .:
  Fly   166 RMYYEPLSNINNEFIERIKE-----IRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKN 225

Human   215 SPSSASLNFLHALEVMFKSTVQLMFMPRSLSRW--------------------TSPKVWKEHFEA 259
            ..:|.:|........:|:.|.:|...|   |.|                    .|.|:.||:.:|
  Fly   226 RDNSDALTLFQTSRDIFRLTFKLDIQP---SMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDA 287

Human   260 WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLL 324
            .:...|.|    :||          ...|::..|:   |:.|......|:::....||.|...|.
  Fly   288 LEKRRQAG----EKI----------NSNSMLERLM---EIDPKVAVIMSLDILFAGVDATATLLS 335

Human   325 MTLFELARNPNVQQALRQESLAAAAS----ISEHPQKATTELPLLRAALKETLRLYPVGLFLERV 385
            ..|..|:::|:.|..||:|.|:...:    ::|...|   ::|.|||.:|||||.||.|....|.
  Fly   336 AVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMK---DMPYLRAVIKETLRYYPNGFGTMRT 397

Human   386 ASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRN-----FYHVPFGF 445
            ..:|::|..|.:|.||.|.:....|.:....:|||:.:.|:|||....:|:.     |..:||||
  Fly   398 CQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGF 462

Human   446 GMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSM-FP 495
            |.|.|:|:|:.:.||...:..::::..||............|::.|:: ||
  Fly   463 GPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP11B1	NP_000488.3	p450	42..454	CDD:365848	101/397 (25%)
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	107/434 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820