Protein Alignment CYP4B1 and Cyp9f2

DIOPT Version :9

• Sequence 1: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 111/452 - (24%)
• Similarity: 186/452 - (41%)
• Gaps: 69/452 - (15%)

Human    85 FGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
            |..||...|::      |..|..||.  |:.:.|    |..|..:...:|...|..|:|.|....
  Fly    97 FDHFINHRNVF------ATSSDDDPH--DMSNLF----GSSLFSMRDARWKDMRSTLSPAFTGSK 149

Human   150 LKPYVAVFTESTRIMLD--KWEEKAREGKSFDI--FCDVGHMALNTLMKCTFGRGDTGLGHSRDS 210
            ::....:..:..:..:|  |.::...:....|:  :|.  ....:.:....||. .......|::
  Fly   150 MRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCT--RFTNDVIASTAFGL-QVNSFKDREN 211

Human   211 SYYLAVSDLTLLMQQRLVSFQYHND--FIYWLTPHG-RRFLRACQVAHDHTDQVIRERKAALQDE 272
            ::|        .|.::|.:|.:...  |:.:....| .:.|:........|...:|   ..|...
  Fly   212 TFY--------QMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVR---LVLDAM 265

Human   273 KVRKKIQNRRHLDFLDILLGAR---DEDDIKL------SDADLRAEVDTFMFEGHDTTTSGISWF 328
            |.|:: .|....|.:::|:.||   ..:..|.      ||.|:.|:...|.|.|.:|     |..
  Fly   266 KYRQE-HNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFET-----SAV 324

Human   329 LYCMALY-----PEHQHRCREEVREILGDQDF----FQWDDLGKMTYLTMCIKESFRLYPPVPQV 384
            |.|...:     .:.|.|..|||:::  |||.    ..::.:..|.||...:.|..|.:|....|
  Fly   325 LMCFTAHELMENQDVQQRLYEEVQQV--DQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAV 387

Human   385 YRQLSKPVTF-VDGRSLPA--GSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP 446
            .|:.:|.:|| |||:.:..  |.:|.:.....||:...:.:|..||..|||.||.....||.:.|
  Fly   388 DRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFP 452

Human   447 FSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR---LPIKM--PQLVLRSKNGFHLHL 503
            |..|.|||||.:||:.|.|.|....|..:.|:  |::   :|:::  ....|..|.||.:.|
  Fly   453 FGLGQRNCIGSRFALLEAKAVIYYLLKDYRFA--PAKKSCIPLELITSGFQLSPKGGFWIKL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	110/448 (25%)
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	110/448 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900