Protein Alignment CYP4B1 and Cyp9h1

DIOPT Version :9

• Sequence 1: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 433
• Identity: 109/433 - (25%)
• Similarity: 179/433 - (41%)
• Gaps: 91/433 - (21%)

Human   122 IGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTES-TRIMLDKWEEKAREG-----KSFDI 180
            :.:.|:.|...:|.:.|.:|||            .||.| .|||.|..:..:.||     :..::
  Fly   118 LSKSLISLRDGRWKEMRNILTP------------AFTGSKMRIMYDLIQSCSEEGVIHIQEQLEL 170

Human   181 FCDVGHMALNTLMKCTFGR------GDTGLGHS------RDSSYYLAVSDLTLLMQQRLVSFQYH 233
            ..|.   ::...||..|.|      .....|.|      :|:.::.....::     |:.::...
  Fly   171 SQDA---SIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMS-----RISAWSVV 227

Human   234 NDFIYWLTPHGRRFLRACQVAH----DHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGAR 294
            ...:|.|.|...:.|| .||..    |:...::.......|:.||.:.       |.:.:|:.|:
  Fly   228 KAMLYALFPRLMKVLR-IQVLDTKNIDYFSSLVTAAMRYRQEHKVVRP-------DMIHLLMEAK 284

Human   295 DEDDIKLSDA-------------DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEV 346
            .:....|||.             ||.|:...|.|.|.:..:|.:.:..:.:.|.|..|.|..||:
  Fly   285 QQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEI 349

Human   347 ----REILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVD--GRSL---PA 402
                .|:.|..  ..:|.|.||.||.|.:.|:.|.:||.....|:..:.:...|  |:.|   ..
  Fly   350 ISVHEELKGQP--LTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARK 412

Human   403 GSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 467
            |.::.:.|::||.:...:.|||.|:..||:..:|.:..  .:|||..|||||||.:.|:.|:|.:
  Fly   413 GDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR--VYMPFGVGPRNCIGNRMALMELKSI 475

Human   468 TAMCLLRFEFSLDPSRLPIKMP--QLV-------LRSKNGFHL 501
            ....||.|:.      ||.|..  .|:       |:.||||.|
  Fly   476 VYQLLLNFKL------LPAKRTSRDLLNDIRGHGLKPKNGFWL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	108/431 (25%)
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	108/431 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900