Protein Alignment CYP4B1 and Cyp9b2

DIOPT Version :9

• Sequence 1: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 455
• Identity: 107/455 - (23%)
• Similarity: 182/455 - (40%)
• Gaps: 57/455 - (12%)

Human    87 QFIGFLN-------IYEPDYAKAVYSRGDPKAPDVYDFFL---QWIGRGLLVLEGPKWLQHRKLL 141
            :.:||.|       :.:|:..|.|..:.....|:...|..   :.....|.|:...:|...|..|
  Fly    70 KLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRNTL 134

Human   142 TPGFHYDVLKPYVAVFTESTRIMLDKWEEKA-----REGKSFDIFCDVGHMALNTLMKCTFGRGD 201
            ||.|....::....:..||....|...:..:     |:|...|:......::.:.:....||...
  Fly   135 TPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKV 199

Human   202 TGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERK 266
            ....:.::..|.:..|   |:..:.|..|::   .:..|.|.....|:.........|...|...
  Fly   200 NSYDNPKNEFYEIGQS---LVFSRGLQFFKF---MLSTLVPKLFSLLKLTIFDSAKVDYFARLVV 258

Human   267 AALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYC 331
            .|:|   .|:| .|....|.:.:|:.|::|.:.|.:|.::.|:...|.|...:..::.|....|.
  Fly   259 EAMQ---YREK-HNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYE 319

Human   332 MALYPEHQHRCREEV---REILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVT 393
            :...|:.|.|..||:   ::.|.... ..:|.:.||||:.|.|.||.|.:.......|..||..|
  Fly   320 LLYNPDVQERLYEEIVETKKALNGAP-LTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYT 383

Human   394 FV--DGRSL---PAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRN 453
            ..  ||..|   ..|..|::.|..||.:...:|:|..||..|||.|......|:.::||..||||
  Fly   384 LTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRN 448

Human   454 CIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-------------PIKMPQLVLRSKNGFHLHLKP 505
            |||.::|:.::|.:....||.::....|..:             |          ::||.:||.|
  Fly   449 CIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTP----------RSGFWMHLVP 503

Human   506  505
              Fly   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	104/449 (23%)
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	101/418 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900