Protein Alignment CYP4B1 and Cyp9b1

DIOPT Version :9

• Sequence 1: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 106/490 - (21%)
• Similarity: 187/490 - (38%)
• Gaps: 74/490 - (15%)

Human    50 PTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPK---- 110
            |..:|...|....:..|..|.:|..:.....|.|     :|..|:..|     :....||:
  Fly    38 PYPFLGNMAASALQKASFQKQISEFYNRTRHHKL-----VGLFNLRTP-----MIQINDPQLIKK 92

Human   111 --APDVYDFF----------LQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRI 163
              ..| :|.|          .:.:...|.|:....|...|.:|||.|....::....:..||...
  Fly    93 ICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQ 156

Human   164 MLD--KWEEKAREGKS-----FDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTL 221
            .|:  |..:....|::     ..:.|:  .::.:.:....||..........:..:.:.   .||
  Fly   157 CLEHLKSSQPIAAGENAFELDMKVLCN--KLSNDVIATTAFGLKVNSFDDPENEFHTIG---KTL 216

Human   222 LMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDF 286
            ...:.|...::   .:..|.|....|.:.......:.:..:|....|:|   .|:| .|....|.
  Fly   217 AFSRGLPFLKF---MMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVDAMQ---YREK-HNITRPDM 274

Human   287 LDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYP-----EHQHRCREEV 346
            :.:|:.|:.|.....:|.::.|:...|.|...:..::     |.|...|.     :.|.|..|||
  Fly   275 IQLLMEAKKESKDNWTDDEIVAQCFIFFFAAFENNSN-----LICTTAYELLRNLDIQERLYEEV 334

Human   347 REILGDQDFFQ-----WDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVD--GRSL---P 401
            :|   .|:..:     :|...:|||:.|.|.||.|.:.......|..:|..|..|  |..|   .
  Fly   335 KE---TQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFK 396

Human   402 AGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466
            ||..|::.|..||.:...:|.|:.||..|||........|:.::||..|||:|||.::|:.:.|.
  Fly   397 AGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKG 461

Human   467 VTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHL 501
            :....:|.::....|     :..:.:..|..||::
  Fly   462 MLYNLMLNYKIEASP-----RTTRDMWESARGFNI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	106/488 (22%)
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	103/475 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900