Protein Alignment CYP4B1 and Cyp4ac2

DIOPT Version :9

• Sequence 1: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 439
• Identity: 128/439 - (29%)
• Similarity: 227/439 - (51%)
• Gaps: 39/439 - (8%)

Human    83 LWFGQFIGFLNIYEPDYAKAVYSRGDPKAPD-VYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFH 146
            ||:.......||...:.|:.:.........: :|:....::|.|||:....||...||.|||.||
  Fly    88 LWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLISTDQKWHSRRKALTPAFH 152

Human   147 YDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDS- 210
            :.||:.::.:|.|....::....:..  ....::...:....||.:  |     :|.||...|.
  Fly   153 FKVLQSFLIIFKEECNKLVKVLHQSV--NMELELNQVIPQFTLNNV--C-----ETALGVKLDDL 208

Human   211 ----SYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD 271
                .|..::..:..:|||||.:..::|...::|....|:.:...::||:.:..:|.:|::..:.
  Fly   209 SEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKS 273

Human   272 EKVRKKIQ--NRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMAL 334
            .::.::.:  .::....||.||.|  |.|.::....:..||:||||||:|||::.:.:.|..:||
  Fly   274 NQLGQEDEFGKKQRYAMLDTLLAA--EADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLAL 336

Human   335 YPEHQHRCREEVREILGDQD---FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVD 396
            :.:.|.:|.||::.:..|.|   .||:::|   .|:...||||.||:|.||.:.|:..:. ..|:
  Fly   337 HEDVQKKCYEEIKYLPDDSDDISVFQFNEL---VYMECVIKESLRLFPSVPFIGRRCVEE-GVVN 397

Human   397 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAM 461
            |..:|..:.|::|:|.:.|::..:.:|::|...||..||...||||||:|||||.||||||:||:
  Fly   398 GLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAI 462

Human   462 SEMKVVTAMCLLRFEFSLDPSRLPIKMPQ-------LVLRSKNGFHLHL 503
            .|:||:.|..:..|:.      ||:.:..       :|||:|....:.|
  Fly   463 LEIKVLLAAVIRNFKI------LPVTLLDDLTFENGIVLRTKQNIKVKL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	127/435 (29%)
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	127/437 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154878
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850