Protein Alignment CYP4A11 and Cyp4ac2

DIOPT Version :9

• Sequence 1: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Sequence 2: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 125/398 - (31%)
• Similarity: 211/398 - (53%)
• Gaps: 24/398 - (6%)

Human   120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLE 184
            |..|.|::|.|||:...|.|...|:.||||||:.:|:.::.:..:....::....:.:..:  ||
  Fly   121 YELLKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNME--LE 183

Human   185 VFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQS--YIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
            :.|.:...||:.:.:.|.    .:::|..|:.  |.|:|..:..::..|:.|.|..|...:.|..
  Fly   184 LNQVIPQFTLNNVCETAL----GVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFG 244

Human   248 AGRWTHRACQLAHQHTDQVIQLRKA-----QLQKEGELEKIKRKRHLDFLDILLLAKMENGSILS 307
            ..|......::||:.:..:|:.|::     ||.:|.|..|.:|...||    .|||...:|.| .
  Fly   245 DYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLD----TLLAAEADGQI-D 304

Human   308 DKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYT 372
            .:.:..||:||||||:|||::.:.:.|..||.|...|::|.|||..|..|...|:....:::.|.
  Fly   305 HQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNELVYM 369

Human   373 TMCIKEALRLYPPVPGIGRE-LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF 436
            ...|||:|||:|.||.|||. :...|.  :|..:||...:.:.:|.:..:.:.:.||::|.|.||
  Fly   370 ECVIKESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRF 432

Human   437 APGSA--QHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIAR-LVLKS 498
            .|.:.  :|..||:|||.|.|||||::||:.|:||..|..:..|::||......:.... :||::
  Fly   433 FPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFENGIVLRT 497

Human   499 KNGIHLRL 506
            |..|.::|
  Fly   498 KQNIKVKL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	124/395 (31%)
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	124/396 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154848
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850