back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GRK3 and YCK3

DIOPT Version :9

Sequence 1:	NP_005151.2	Gene:	GRK3 / 157	HGNCID:	290	Length:	688	Species:	Homo sapiens
Sequence 2:	NP_011049.2	Gene:	YCK3 / 856860	SGDID:	S000000925	Length:	524	Species:	Saccharomyces cerevisiae

Alignment Length:	376	Identity:	77/376 - (20%)
Similarity:	124/376 - (32%)	Gaps:	143/376 - (38%)

- Green bases have known domain annotations that are detailed below.

Human   185 HLTMNEFSVHRIIGRGGFGEVY-------GCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIM 242
            |:....::|...||.|.||.::       .| :|.||             ..:....:..||.:.
Yeast     8 HIVGIHYAVGPKIGEGSFGVIFEGENILHSC-QAQTG-------------SKRDSSIIMANEPVA 58

Human   243 LSLVST-GDCPFIVCMTYAFHTPDKLCFILDLMNG--GDLH-YHLSQHGV--------------- 288
            :..... .|.|.:.....|:.          ::||  |..| |:..|.|:
Yeast    59 IKFEPRHSDAPQLRDEFRAYR----------ILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLED 113

Human   289 --------FSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARIS----------- 334
                    ||.|.....|.::|..:..:|:..::|||:||.|.|:.:  :.|||
Yeast   114 LFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQ--YQRISPEGKVIKSCAS 176

Human   335 ------------DLGLACDF--SKKKPH-------ASVGTHGYMAPEVLQKGTAYDSSADWFSLG 378
                        |.|:|..:  .:.|.|       :..||..||:... ..|.......|..|||
Yeast   177 SSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINT-HFGREQSRRDDLESLG 240

Human   379 CMLFKLLRGHSPFRQHK---TKDKHEIDRMT--------LTVNVELPDTFSPELK---------- 422
            .:.|..|||..|::..|   .|.|:|...||        |.:|..:|..|:..||
Yeast   241 HVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDED 305

Human   423 -------SLLEGLLQRD----------------------VSKRLGCHGGGS 444
                   ||::..|:.:                      :::|...||.|:
Yeast   306 PDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGN 356

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.