Protein Alignment Runx3 and RunxA

DIOPT Version :9

• Sequence 1: NP_569109.1
• Gene: Runx3 / 156726
• RGDID: 620082
• Length: 409
• Species: Rattus norvegicus
• Sequence 2: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 394
• Identity: 153/394 - (38%)
• Similarity: 190/394 - (48%)
• Gaps: 88/394 - (22%)

  Rat    54 RSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENY 118
            |::.|.|.:|.|||:||.||.|:|:|||.|||.|||||||||||:|||:.|||:|||.|||||||
  Fly    86 RTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENY 150

  Rat   119 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPR- 182
            .|||||.:||||||||:||||||||||||||||||||||.|||..:|||::|||||||||||||
  Fly   151 CAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPRS 215

  Rat   183 RHRQKIEDQTKAFPDRFGDLRMRVTPSTPSPRGSLSTTSHFSSQAQTPIQGSSD-LNPFSDPRQF 246
            :....:..|.:.|...||                           |.|...|:| |:.|..|
  Fly   216 KTMLSLLGQQQQFHFAFG---------------------------QRPFHFSTDPLSGFRMP--- 250

  Rat   247 DRSFPTLQSLTESRFPEGRMHYPGAMSAAFPYSATPSGTSLGGLSVAGMPASSRFHHTYLPPPYP 311
              .....||.:.:.:     .|..|.||..||.|:      .|||....|.|::|::..|.....
  Fly   251 --PIGNCQSASNTHW-----GYGSAASAYSPYLAS------SGLSSCTTPTSAQFNNPALGFTCS 302

  Rat   312 GAPQSQSGPF---------------QANPAPYHL--FYGTSSGSYQFSMAAAGGGERSPTRMLTS 359
            ...||.:..|               .|:....||  ..|::||..........||:.|.:..:..
  Fly   303 SNDQSNNQDFGGATNRDCVPMLPDSTASDLDQHLSSLVGSTSGQMTHHSLLGAGGQTSISSTVNG 367

  Rat   360 CPTGASVSAGNLMNPSLGQADGVEADG-----------------------SHSNSPTALSTPGRM 401
            ...|.|..||....   |...|..|.|                       |..|.|.:||...:.
  Fly   368 ASGGGSAGAGTAGG---GAGSGGGAGGGAGGNSILVPRYHTNASNEYNVHSSQNGPRSLSDSSQA 429

  Rat   402 DEAV 405
            :..|
  Fly   430 ESPV 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Runx3	NP_569109.1	Runt	63..184	CDD:279225	97/121 (80%)
		RunxI	314..409	CDD:285676	26/132 (20%)
RunxA	NP_001259747.1	Runt	95..216	CDD:279225	97/120 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3567
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm8944
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060