DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elavl2 and Rbp9

DIOPT Version :9

Sequence 1:	XP_036019590.1	Gene:	Elavl2 / 15569	MGIID:	1100887	Length:	530	Species:	Mus musculus
Sequence 2:	NP_001259974.1	Gene:	Rbp9 / 33498	FlyBaseID:	FBgn0010263	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	243/453 - (53%)
Similarity:	290/453 - (64%)	Gaps:	46/453 - (10%)

- Green bases have known domain annotations that are detailed below.

Mouse    91 RQQPVGRAGFRRVPVRLPAAASVTPLSGAVGRRREPWELQPSRSRR----QLQTNMAVRLCDVAS 151
            :|||.|..|          |:.|...:|:.|        .|:.:..    |.|||........|:
  Fly    12 QQQPSGAGG----------ASGVGSTTGSAG--------GPATANNVTNSQAQTNGGTTATTTAA 58

Mouse   152 LLRSGSWAAEPWTGQVIA--AMETQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVN 214
             ..:|| ......||..|  |.....:|....||..|...|.|||      :.|..|.|||||||
  Fly    59 -AGAGS-TTNAAVGQATANNAASNNNNNNNNTNNNNNNNATANNN------NNNEPDPKTNLIVN 115

Mouse   215 YLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 279
            ||||.|:|:|::|||.|.||:|||||:|||:||||||||||||:..:|||||||.|||||||.||
  Fly   116 YLPQTMSQDEIRSLFVSFGEVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNGLRLQNKT 180

Mouse   280 IKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 344
            ||||.|||||.||:.||||||||||.|||.:||.|||.||:|||||||.|.:||:|:||||||||
  Fly   181 IKVSIARPSSESIKGANLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKGVGFIRFD 245

Mouse   345 KRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSP-----NRRYPGPLAQQA 404
            :|.||:.|||.|||..|..:|||||||||||||...|.......|.:|     .|.:|...|..|
  Fly   246 QRFEADRAIKELNGTTPKNSTEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFPANAAAGA 310

Mouse   405 QRFRLDNLLNMAYG----VKSRFSPMTIDGMTS--LAGINIPGHPGTGWCIFVYNLAPDADESIL 463
            ........::...|    |.||:||:|.|.:|:  :.|..|   ..:||||||||||||.:|::|
  Fly   311 AAAAAAAAIHPNAGRYSSVISRYSPLTSDLITNGMIQGNTI---ASSGWCIFVYNLAPDTEENVL 372

Mouse   464 WQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 526
            ||:|||||||.:||||||..:||||||||||||||:||.:||.|||||.||:|||||||||||
  Fly   373 WQLFGPFGAVQSVKVIRDLQSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNK 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elavl2	XP_036019590.1	ELAV_HUD_SF	206..529	CDD:273741	213/332 (64%)
Rbp9	NP_001259974.1	ELAV_HUD_SF	107..438	CDD:273741	213/332 (64%)
		RRM1_Hu	109..186	CDD:241094	60/76 (79%)
		RRM2_Hu	196..274	CDD:241096	56/77 (73%)
		RRM3_Hu	355..432	CDD:240823	60/76 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850001
Domainoid	1	1.000	121	1.000	Domainoid score	I5668
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	420	1.000	Inparanoid score	I1774
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	1	1.000	-	-		mtm8744
orthoMCL	1	0.900	-	-		OOG6_103306
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760