| Sequence 1: | NP_032328.2 | Gene: | Hsp90ab1 / 15516 | MGIID: | 96247 | Length: | 724 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_651601.1 | Gene: | Gp93 / 43354 | FlyBaseID: | FBgn0039562 | Length: | 787 | Species: | Drosophila melanogaster |
| Alignment Length: | 733 | Identity: | 337/733 - (45%) |
|---|---|---|---|
| Similarity: | 485/733 - (66%) | Gaps: | 43/733 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKID 74
Mouse 75 IIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQ-----AGADIS-MIGQFGVGF 133
Mouse 134 YSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERR 197
Mouse 198 VKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSG 262
Mouse 263 KDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQL 327
Mouse 328 EFRALLFIPRRAPFDLFEN-KKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNIS 391
Mouse 392 REMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLR 456
Mouse 457 YHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYC 521
Mouse 522 VQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEI-LDKKVEKVTISNRLV 585
Mouse 586 SSPCCIVTSTYGWTANMERIMKAQALR---DNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKN 647
Mouse 648 DKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE---------------VTA 697
Mouse 698 EEPSAAVPDEIPPLEGDE 715 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hsp90ab1 | NP_032328.2 | Interaction with TP53. /evidence=ECO:0000250|UniProtKB:P08238 | 2..527 | 262/524 (50%) | |
| Interaction with BIRC2. /evidence=ECO:0000250|UniProtKB:P08238 | 2..214 | 113/210 (54%) | |||
| Interaction with NR3C1. /evidence=ECO:0000269|PubMed:27686098 | 9..231 | 117/227 (52%) | |||
| HSP90 | 14..724 | CDD:332554 | 336/729 (46%) | ||
| Interaction with AHSA1. /evidence=ECO:0000250|UniProtKB:P08238 | 215..552 | 161/337 (48%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..270 | 17/47 (36%) | |||
| Interaction with NR3C1. /evidence=ECO:0000269|PubMed:27686098 | 264..608 | 169/345 (49%) | |||
| Interaction with NR1D1. /evidence=ECO:0000269|PubMed:27686098 | 620..723 | 36/111 (32%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 694..724 | 7/37 (19%) | |||
| TPR repeat-binding | 720..724 | ||||
| Gp93 | NP_651601.1 | PRK05218 | 74..745 | CDD:235366 | 326/686 (48%) |
| HATPase_c | 97..216 | CDD:238030 | 69/118 (58%) | ||
| HSP90 | 257..748 | CDD:278607 | 227/505 (45%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0326 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D174605at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000295 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100204 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X234 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.720 | |||||