Protein Alignment CYP3A7 and Cyp4ac3

DIOPT Version :9

• Sequence 1: NP_000756.3
• Gene: CYP3A7 / 1551
• HGNCID: 2640
• Length: 503
• Species: Homo sapiens
• Sequence 2: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 407
• Identity: 110/407 - (27%)
• Similarity: 195/407 - (47%)
• Gaps: 48/407 - (11%)

Human   113 FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFG 177
            |:.:.:.|:.|::|...|..|:|.|....|:..:.|..:.....::.|  :...|..:.|..:..
  Fly   126 FLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKIL--DKNVGFELELNQIIP 188

Human   178 AYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRF---------NPLDPF------VLSIKVFP 227
            .::::.|..|:.||.:|.::...    |..|.:..|         |||..|      ....|.:.
  Fly   189 QFTLNNICETALGVKLDDMSEGN----EYRKAIHDFEIVFNQRMCNPLMFFNWYFFLFGDYKKYS 249

Human   228 FLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSE---THKA 289
            .:...:...:..:..||...|..|.:.|:.|...|:.        ..|:|:..:.::|   .|:.
  Fly   250 RILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQR--------YAMLDTLLAAEAEGKIDHQG 306

Human   290 LSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--- 351
            :.|     :...|:|.||:|||:.|.|.:..||.|.|||::..:|:..:     |...|.|.
  Fly   307 ICD-----EVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDL-----PEDIDEVSMFQ 361

Human   352 --QLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKF 414
              :|.:|:.|:.|:|||||.|..:.|.|.::..:||:.:||...:.|..|.:..|.:::.:|.:|
  Fly   362 FNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQF 426

Human   415 LPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRF 479
            |||||..:|..|..|:.:.||.:|||||||.:|.::.:|:.|..|::||...|..:.: .|....
  Fly   427 LPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLE-DLTFEN 490

Human   480 GGLLLTEKPIVLKAESR 496
            |.:|.|::.|.:|.|:|
  Fly   491 GIVLRTQQNIKVKFEAR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP3A7	NP_000756.3	p450	39..492	CDD:365848	107/401 (27%)
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	107/402 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910