Protein Alignment Hsf2 and Hsf

DIOPT Version :9

• Sequence 1: XP_006512627.1
• Gene: Hsf2 / 15500
• MGIID: 96239
• Length: 535
• Species: Mus musculus
• Sequence 2: NP_001036555.1
• Gene: Hsf / 37068
• FlyBaseID: FBgn0001222
• Length: 733
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 176/673 - (26%)
• Similarity: 296/673 - (43%)
• Gaps: 192/673 - (28%)

Mouse     5 SNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYG 69
            |.|||||:|||.||::..||..|.|:::||||::.::.:||||:||..:||||||||:|||||||
  Fly    44 SGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYG 108

Mouse    70 FRKVVHIESGIIKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK--IRQEDLTKIISS 132
            |.|:..|::|.::.:|| .:||.||:||:....||:.||||:|::|..::|  ::.|.::||::.
  Fly   109 FHKITSIDNGGLRFDRD-EIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKPEAMSKILTD 172

Mouse   133 AQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVS-LKR 196
            .:.::.:|:.::||.|.:|.|||.||:|::.||.|||:|||::.|::||::|:||.::.:| :||
  Fly   173 VKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKR 237

Mouse   197 KRPLLLN-----------------TNGAP-----KKNLYQHI----------------------- 216
            ...|::|                 :.|.|     ::.|...:
  Fly   238 HVQLMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPA 302

Mouse   217 VKEPTDN---HHHKVPHSRTEG----LKSRERISDDII--------------------IYDVT-- 252
            |:.|..|   ..|.|.:|....    |:.......:|:                    :|.||
  Fly   303 VERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEA 367

Mouse   253 -DDNV----------DEENIPVIPETNE--------------------DVVVDSSNQYPDIVIVE 286
             |.:|          :|:|:...|...|                    ||::|:.:     ::|:
  Fly   368 PDSHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQQLKENNKLRRQAGDVILDAGD-----ILVD 427

Mouse   287 DDNEDEYAPVIQSGEQSEPAREPLRVGS-AGSSSPLMSSAVQLNG--SSSLTSEDPVT--MMDSI 346
            ..:.......||...|.:...:|:.:.| ..:||.||......|.  |.:..|||..|  ..|::
  Fly   428 SSSPKAQRTSIQHSTQPDVMVQPMIIKSEPENSSGLMDLMTPANDLYSVNFISEDMPTDIFEDAL 492

Mouse   347 LNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDL-----LVDLFTSS---------- 396
            |.|.:....|         :|...:..|:.:|..:|:.:.|:     |:|...:|
  Fly   493 LPDGVEEAAK---------LDQQQKFGQSTVSSGKFASNFDVPTNSTLLDANQASTSKAAAKAQA 548

Mouse   397 --------VQMNPTDNINNTKSENKGL----------EATKSSVVQHVSEEGRKSKSKPDK---- 439
                    .:.:..:|.||..:.|..|          :.|.||.:.|  .:...|....|:
  Fly   549 SEEEGMAVAKYSGAENGNNRDTNNSQLLRMASVLVDQKNTNSSRISH--NQAANSYCCSDELHGH 611

Mouse   440 -QLIQYTAFPLLAFLDGNSASAIEQGSTTASSEVVPSVDKPIEVDELL-----DSSL-------- 490
             :.:|.....|...|.|:.. ||:|.....:....|:...|  .||||     ||.|
  Fly   612 LESMQDELETLKDLLRGDGV-AIDQNMLMGALSRTPNFQLP--EDELLLKLFNDSDLMDNYGLSF 673

Mouse   491 --------DPEPTQSKLVRLEPL 505
                    ...|:.|:|:..:|:
  Fly   674 PNDSISSEKKAPSGSELISYQPM 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsf2	XP_006512627.1	HSF	6..110	CDD:214654	55/103 (53%)
		Vert_HS_TF	230..511	CDD:368967	74/397 (19%)
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	55/103 (53%)
		Vert_HS_TF	<607..711	CDD:284062	20/93 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845779
Domainoid	1	1.000	126	1.000	Domainoid score	I5384
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm43811
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2153
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840