Protein Alignment Hsd3b1 and CG8306

DIOPT Version :9

• Sequence 1: NP_001291729.1
• Gene: Hsd3b1 / 15492
• MGIID: 96233
• Length: 373
• Species: Mus musculus
• Sequence 2: NP_611140.3
• Gene: CG8306 / 36857
• FlyBaseID: FBgn0034142
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 107/510 - (20%)
• Similarity: 180/510 - (35%)
• Gaps: 199/510 - (39%)

Mouse     2 AGWSCLVTGAGGFVGQRIIKMLVQE----------------KELQEVRALDKVFRPETKEEFSKL 50
            ||.:..:|||.||||..|::.|:::                |.:||  .|:::.:....::|.:|
  Fly    11 AGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQE--RLEELKKNSVFDKFKEL 73

Mouse    51 QTK---TKVTVLEGDI---------LDAQCLRRACQGISVVIHTAAVIDVTGVIPRQTILDVNLK 103
            |.:   :|:..:|||:         .|.|.|   ...::||.|:||.:|....:...|  ::||:
  Fly    74 QLQSRLSKIVPIEGDVGLEHLGISPKDRQTL---IDNVNVVFHSAATLDFFQSLKETT--NINLR 133

Mouse   104 GTQNLLEACVQ-ASVPAFIFCSSVDV------------AGPNSYKKIV-------------LNGH 142
            ||:.::|.|.| .::.|.:..||..|            ..|...:||:             |...
  Fly   134 GTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPK 198

Mouse   143 EEQNHESTWSDPYPYSKKMAEKAVLAAN-----------GSML--------------KNG----- 177
            ..::|.:|    |.::|.:||..|  ||           .||:              |||
  Fly   199 LLKDHPNT----YTFTKHLAEHEV--ANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFF 257

Mouse   178 -----GTLNTCALRPMYIYGERSPF--IFNAIIRALKNKGILCVTGKFSIANPVYVEN------V 229
                 |.|....|.|..|. :..|.  :.|.||          .||.:  .|.:..:|      :
  Fly   258 MGASKGVLRRLPLDPSIIM-DYIPIDVVVNGII----------TTGYY--VNSLQAKNGGRPADL 309

Mouse   230 AWAHILAARGLRDPKKSTSIQGQFYYISDDTPHQSYDDLNYTLSKEWGLRPNASW--SLPLPLLY 292
            ...|:.:         ||....:|..::|......:|   |.|:       :|.|  :|.|....
  Fly   310 QIFHLTS---------STYKPFRFELMTDKINSYLHD---YPLN-------SAVWYPNLRLVKSL 355

Mouse   293 WLAFLLETVSF---------LLRPVYRYRPLF-------------------------NRHLITLS 323
            |: |.|..:.|         |:..:...||:.                         ::.|:.||
  Fly   356 WV-FRLSAILFHFIPAIILDLVTKIGGGRPILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALS 419

Mouse   324 NSTFTFSYKKAQRDLG--------------------YEPLVNWEEAKQKTSEWIG 358
            .:......||...|:|                    .||:.|.|:|::|....:|
  Fly   420 KTLNIVDKKKFFIDIGELAWDEYFSNTILGVRQYLSKEPIKNLEKARRKDKILLG 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsd3b1	NP_001291729.1	NADB_Rossmann	5..357	CDD:389744	104/504 (21%)
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	100/490 (20%)
		FAR-N_SDR_e	13..339	CDD:187547	78/363 (21%)
		FAR_C	364..454	CDD:176924	11/89 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3985
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860