Protein Alignment IQUB and CG13855

DIOPT Version :10

• Sequence 1: NP_849149.3
• Gene: IQUB / 154865
• HGNCID: 21995
• Length: 791
• Species: Homo sapiens
• Sequence 2: NP_651037.1
• Gene: CG13855 / 42629
• FlyBaseID: FBgn0038960
• Length: 706
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 202/728 - (27%)
• Similarity: 331/728 - (45%)
• Gaps: 105/728 - (14%)

Human    83 ISPRQVSYTPQHHEKQYAMQRPNDDSLAFLDKIKSVKESLQESVEDSLATVKVVLIPVGQEIVIP 147
            :..|.....|||.|          :....|:.: :||..|.:|  :.||.|....:.:|:
  Fly    34 LDSRSTESEPQHSE----------ECCVELENV-TVKFRLSDS--EILAQVYPNCMLLGE----- 80

Human   148 FKVDTILKYLKDHFSHLLGIPHSVLQIRYSGKILKNNETLVQHGVKPQEIVQVEIFSTNPDLYPV 212
                     :|...:....:....|.:|...:||.|:               |.:.||..|.:.:
  Fly    81 ---------IKQDLARKFEVAPEWLVLRQDNRILCNS---------------VPLNSTALDEFGI 121

Human   213 RRI------DGLTD---------------VSQIITVTV-----QTGLDQYQQVPVEIVKSDFHKP 251
            ...      :|..|               ::..|||.:     |.|  |.:.|.|||..:...||
  Fly   122 HEFQLEMNKEGREDQTSKLDLDVYYDKHRLADFITVHISGDDTQDG--QSKTVVVEIENAAIVKP 184

Human   252 FLGGFRHKVTGVEYHNAGTQTVP--KRIPERLSIFCRDTQTVFQKKNLQQTTNTTSTQMTNIGV- 313
            ||.|:|.:.||.||.:|.|||.|  .::..| ....|||||..||:....|.:..|.|....|:
  Fly   185 FLCGYRDQKTGKEYLDAFTQTGPYFDKMKYR-KYKTRDTQTWEQKEKTLNTAHEQSVQCHLDGIN 248

Human   314 --YVSNMTDKLVTPGKY--FSAAEYHAQRLKAVIVIQTYYRQWHAKIFVENLRRQKSLRLEWETQ 374
              |||...|..:.||||  |:..|...::|:.:::||..:|:|....:: :||.|:..||....:
  Fly   249 ILYVSAANDFTIVPGKYQTFAQKERAERKLEKILLIQRNWRRWILWKYI-HLRAQEYRRLVQNRE 312

Human   375 QELRKIREKEEWIKLDYHR--RHNPKTNEDFEFLYNALEFWRQEELTRINQSFTGAERKAALCEL 437
            .|..:..:..|. :::.||  :..|:..:||:.||..:..|::.||.||..::.|..|.|.:..|
  Fly   313 HEDERYEKCVEQ-RMERHRVIKQFPRNKDDFDLLYAEVARWKKAELKRITANYEGPARIAEVNIL 376

Human   438 LEKETQIIASIGRHRYIAYMANQEAAIQAFLDKCSAPKIWRTPNGKTIEMDTQFTIRARELQNIY 502
            |:||.|::..:.|.|.:.|.|.::......|.:...|..|.......|.||...|.|.|.|..||
  Fly   377 LDKEIQLLNGVERQRNLVYKAMEDFRKDQLLKEMGKPIEWVGYKDSKIHMDLLSTQRVRFLTEIY 441

Human   503 KCIMLKNISQDERLDVLLTLKHTVKEHEC-KLTQEILELIDREVDLMMRGVKHHNLEGLRKRIAT 566
            |.:. |..|:::|||.:..:...:.|..| ....|:.:|.|||.:|::. .|..::|.||||...
  Fly   442 KDLR-KPRSKEDRLDFIRQVMAVLTEETCFPHFPELFDLFDREKNLLLY-AKSFDVEILRKRQTM 504

Human   567 LFFHYIKTPLFNPEVAKYLKVPQDPLKFYKKIYFCHSCQLYLPSTEFSVSSTSRRIYRCRNCINL 631
            |||..||.....|:    .::|.         ..|..|:......||::.:....:..|::|..|
  Fly   505 LFFDLIKFQKGEPK----QRIPS---------RMCIVCKKVKTYAEFAIRTRQSHVDTCKHCYYL 556

Human   632 QNEAQKRESFLKYKCLLQQLYYTEADYEDDSKIAFLMQLQDIQYLTENIWASQSVLSACDNLSDL 696
            :..|.:.   ..|:.:|:.::..|...:..:..||:||..|::::.:.||...|.||..:|||:|
  Fly   557 KLTATEN---TVYQSILRCIHRDERKRKCTTSFAFVMQPDDVRHIIDKIWHGHSALSKTENLSEL 618

Human   697 VMVRWNKSLEWSPWNCILLTKDEAAAHLKLTSIEEGYERSFIHKIKHKHILAKNYFSQVPVLASF 761
            .:.|||||.:|:|||||.||:.|...|.|:..||:.|:..|:..|.:.|:||::.|..:..:|:.
  Fly   619 RLPRWNKSDDWAPWNCICLTERETRDHYKIDDIEKVYDPKFVLHIGNLHMLARSLFHTLAAVATE 683

Human   762 ILDDGEIDEIRWK 774
            ..:.|:    .||
  Fly   684 FQETGQ----WWK 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IQUB	NP_849149.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73
		Ubl_IQUB	129..207	CDD:340581	13/77 (17%)
CG13855	NP_651037.1	None