Protein Alignment Hsd11b2 and CG8888

DIOPT Version :9

• Sequence 1: NP_032315.2
• Gene: Hsd11b2 / 15484
• MGIID: 104720
• Length: 386
• Species: Mus musculus
• Sequence 2: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 366
• Identity: 105/366 - (28%)
• Similarity: 160/366 - (43%)
• Gaps: 52/366 - (14%)

Mouse    29 RLGRPLL----AALA---LLAALDWLCQRLLPPPAALVVLAGAGWIALSRLARP-----PRLPVA 81
            ||..|.|    ||:.   ||.|||         .:::...|...|.||:.:...     .::..:
  Fly    39 RLFMPFLFCQAAAIVTSHLLHALD---------ISSISTFAVFVWFALATVGAVLFYHFVKVSAS 94

Mouse    82 TRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNSP-----GALELRDLCSPRLKLLQMDLTK 141
            .:.||||||:.......|||||.:||||.|   ..|:|     .|..|:::.|.|:|||.:|:|.
  Fly    95 GKGVLITGCEAPLAWYLAKKLDDLGFTVYA---GFNTPIEESDEAKILKEVTSGRMKLLHLDVTS 156

Mouse   142 AEDISRVLEITKAHT--ASTGLWGLVNNAGLNIVVADVELSPVATFRKCMEVNFFGALELTKGLL 204
            .:.|.........|.  .:.|||.:|:.|.. |.:.::|..|.|..||.:::|..|:..||:..|
  Fly   157 EKTILEAARYVSQHLPHGAEGLWSVVHCAHW-IALGELEWIPFAVLRKSLDLNLLGSARLTQIFL 220

Mouse   205 PLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFGCELLPWGIKVSIIKPGCFK--T 267
            ||:|.:.||:|.:.|....:|.|.......::||:.........|:...|:.||::..|.|.  .
  Fly   221 PLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFAPGN 285

Mouse   268 DAVTNVNLWEKRKQLLLANIPRELLQAYGEDYIEHVHGQFLNSLRMALPDLSPVVDAIIDALLAA 332
            ..:....|.::.|| :...:..|..:.|||||.|..........|.| .|:.|.:..:|||:...
  Fly   286 GWLNETELRDQAKQ-MWNQLSSEQKKTYGEDYYEAAMTSVEKYSRQA-ADIQPTLRVLIDAVTRT 348

Mouse   333 QPRSRYYPGRGLGLMYFIHHYLPEGLRRCFLQNFFINHLLP 373
            .|.:||.|             :....|   ||.|...||.|
  Fly   349 FPMARYTP-------------VTSSER---LQIFLAEHLAP 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsd11b2	NP_032315.2	type2_17beta_HSD-like_SDR_c	83..363	CDD:187665	84/288 (29%)
		adh_short	83..278	CDD:278532	63/203 (31%)
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	90/300 (30%)
		adh_short	96..293	CDD:278532	62/200 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5728
eggNOG	1	0.900	-	-		E1_KOG1610
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1882
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850