DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxd8 and Ubx

DIOPT Version :9

Sequence 1:	NP_032302.2	Gene:	Hoxd8 / 15437	MGIID:	96209	Length:	289	Species:	Mus musculus
Sequence 2:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	95/271 - (35%)
Similarity:	113/271 - (41%)	Gaps:	72/271 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    17 AAAAAAAAAAAAGEAINPT----------YYDCHFAPEVSGRHAAALQLYGNSAAGFPHAHPHPH 71
            ||.|......|.|..:.|:          |.|......||.|        |.||.|
  Fly   138 AANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHR--------GGSAGG--------- 185

Mouse    72 PHPSPPPGCGGGGGPGPGQDYFHAGAG---------SPTAAYQAAPPPPHPPPPPPPPPCGGIA- 126
             :.|...|.|..||...|...  ||||         |..||..||....|........|...||
  Fly   186 -NVSVSGGNGNAGGVQSGVGV--AGAGTAWNANCTISGAAAQTAAASSLHQASNHTFYPWMAIAG 247

Mouse   127 -CHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFP-WMRP 189
             |..:|.|              ::..::|.||       |.|..|.......|....:.| |:..
  Fly   248 ECPEDPTK--------------SKIRSDLTQY-------GGISTDMGKRYSESLAGSLLPDWLGT 291

Mouse   190 QAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKE- 253
            ...  ||||||||:|:|||||||||..|.||||:||||::|.|.|||||:||||||||||.|||
  Fly   292 NGL--RRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEI 354

Mouse   254 ------NNKDK 258
                  |.::|
  Fly   355 QAIKELNEQEK 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxd8	NP_032302.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	62..125		18/71 (25%)
		COG5576	139..272	CDD:227863	58/128 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..184		4/21 (19%)
		Antp-type hexapeptide	183..188		2/5 (40%)
		Homeobox	199..251	CDD:278475	40/51 (78%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..289		4/14 (29%)
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	40/52 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810