Protein Alignment Hoxb6 and E5

DIOPT Version :10

• Sequence 1: XP_006532355.1
• Gene: Hoxb6 / 15414
• MGIID: 96187
• Length: 309
• Species: Mus musculus
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 80/327 - (24%)
• Similarity: 112/327 - (34%)
• Gaps: 102/327 - (31%)

Mouse     8 NNLSLKSEKGK---RRLSGWDNIIWKLKKIPNAPLSLPPHPFESGGGQNPPSSAKARRSDYKTQQ 69
            ||...::.:|.   ||....|    :.:....:|:|..|.|..:||  ||.::....:|...:..
  Fly    90 NNSGRRTPRGYIYCRRRDSLD----RSRSPQRSPVSRSPSPPNAGG--NPAAAGNTAKSGDPSSG 148

Mouse    70 IINPAEQQRPRAPPLPMSSYFVNSTFPVTLA----------SGQESFLG---------------- 108
            ..||....||...|.|..:...|.|.|..:|          |....||.
  Fly   149 TGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQ 213

Mouse   109 ------QLPLYSSGYADPLRHYPAPYGPGPGQDKGFAASSYYPPAGGGYGRAAPCDYGPAPAFYR 167
                  |||...:|         .|:||.|....|......:|.             ||.|.
  Fly   214 QQQQQQQLPPVPTG---------PPHGPHPHLPPGQIPLGIFPG-------------GPHPG--- 253

Mouse   168 EKDAACALSGADEPPP--FHPEPRKSDCAQDKSVFGETEEQ-KCSTPVYPWMQRMNS------CN 223
                        .|||  .||             ||..... :.|.|:|||:...:.      ..
  Fly   254 ------------HPPPHGHHP-------------FGSAPHLIRDSYPLYPWLLSRHGRIFPRFPG 293

Mouse   224 SSSFGP--SGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 286
            :..|.|  ..:|.|..::..|.|:||..|..|.|:....|.::|..|.|||.|:|:||||||.|.
  Fly   294 NFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKH 358

Mouse   287 KK 288
            |:
  Fly   359 KR 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb6	XP_006532355.1	Homeodomain	232..288	CDD:459649	24/55 (44%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	24/55 (44%)