Protein Alignment Hoxb6 and cad

DIOPT Version :10

• Sequence 1: XP_006532355.1
• Gene: Hoxb6 / 15414
• MGIID: 96187
• Length: 309
• Species: Mus musculus
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 363
• Identity: 85/363 - (23%)
• Similarity: 127/363 - (34%)
• Gaps: 110/363 - (30%)

Mouse     9 NLSLKSEKGKRRLSGWDNIIWKLKKIPNAPLSLPPHPF--ESGGGQNPPSSAKARRSDYKTQQII 71
            ||:..|..|:    .|:   |    .||...:.|.|.|  :.........:|.|.:..|.:..:.
  Fly    19 NLAYASAAGQ----PWN---W----TPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMF 72

Mouse    72 NPAEQQRPRAPPLPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDK 136
            :.|..........|.|             |..::|:..:|..:........|:.| :........
  Fly    73 HSAAAASAGEWHSPAS-------------STADNFVQNVPTSAHQLMQQHHHHHA-HASSSSASS 123

Mouse   137 GFAASSYYP---------------PAGGGYGRAAPCDYGP--APAFYREKDAACALSGADEPP-- 182
            |.::|...|               .||||.|.....|.||  ||..:::..|    .|...||
  Fly   124 GSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIA----EGLPSPPIT 184

Mouse   183 -----------------PFH----------------------PEPRKSDCAQDKSVFGETEEQKC 208
                             |.|                      |....:: ..:.||.........
  Fly   185 VSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNN-NNNNSVSNNNRTSPS 248

Mouse   209 STPVYPWMQR-----------MNSCN----SSSFGPSGR-----RGRQTYTRYQTLELEKEFHYN 253
            ..|.:.||::           .:|.|    |.....||:     :.|..||.:|.||||||:..:
  Fly   249 KPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTS 313

Mouse   254 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESK 291
            ||:|.||:.|:|..|.|:|||:||||||||.|.:|::|
  Fly   314 RYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNK 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb6	XP_006532355.1	Homeodomain	232..288	CDD:459649	31/60 (52%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	31/54 (57%)