Protein Alignment Hoxb5 and Ubx

DIOPT Version :10

• Sequence 1: NP_032294.2
• Gene: Hoxb5 / 15413
• MGIID: 96186
• Length: 269
• Species: Mus musculus
• Sequence 2: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 109/405 - (26%)
• Similarity: 139/405 - (34%)
• Gaps: 159/405 - (39%)

Mouse     1 MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSH 65
            |:|||..: ||.|  |..:|......|   ||.:.|..|....:   .|.|..||:..|..::.|
  Fly     1 MNSYFEQA-SGFY--GHPHQATGMAMG---SGGHHDQTASAAAA---AYRGFPLSLGMSPYANHH 56

Mouse    66 FGAVGESSRAFPASAQEPRFRQATSSCSL-----SSPESLPCTN---------------GDSHG- 109
            .....:.|         |.....|::|:.     :......|.|               |.|:|
  Fly    57 LQRTTQDS---------PYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKDIWNTGGSNGG 112

Mouse   110 ----------------------------------------AKPSASSPSDQ---------ATPAS 125
                                                    .:|||.:|..:         .:|.|
  Fly   113 GGGGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVS 177

Mouse   126 ---SSANFTEIDEASASSEPEEAASQLSSPSLARAQP--------EPMATSTAAP----EGQTPQ 175
               .||.    ...|.|.....|....|...:|.|..        ...|..|||.    :.....
  Fly   178 HRGGSAG----GNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHT 238

Mouse   176 IFPWM----------RKLHISHDMT--------------------------GPDG--KRARTAYT 202
            .:|||          .|..|..|:|                          |.:|  :|.|..||
  Fly   239 FYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYT 303

Mouse   203 RYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD--------------N 253
            ||||||||||||.|.|||||||||:||||||:||||||||||||||.||:              .
  Fly   304 RYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQ 368

Mouse   254 KLKSMSLATAGSAFQ 268
            ..|:.:.|.|.:|.|
  Fly   369 AQKAAAAAAAAAAVQ 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb5	NP_032294.2	PRK07003	<67..>171	CDD:235906	27/188 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..173		26/182 (14%)
		Antp-type hexapeptide	176..181		3/14 (21%)
		Homeodomain	195..251	CDD:459649	46/55 (84%)
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	46/55 (84%)