Protein Alignment Hoxb4 and HGTX

DIOPT Version :10

• Sequence 1: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 62/269 - (23%)
• Similarity: 95/269 - (35%)
• Gaps: 80/269 - (29%)

Mouse     9 NSNYVDPKF------PPCE----------------EYSQSDYLPSDHSPGYYAGGQRRESGFQPE 51
            |:|::|.|.      ||..                ..:.::.|...|||..:....|...|....
  Fly   280 NNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSS 344

Mouse    52 AAFGRRAPCTVQRYAACRDPGPPPPP------PPPPPPPPPGLS-------PRAPVQPTAGALLP 103
            ::         .........|.|.|.      ..|||....|||       ||..:...|..:..
  Fly   345 SS---------TTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQ 400

Mouse   104 EPGQRSEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYP-----------WMRKVHVSTVNPNYA 157
            ...|...|             ||.....|...:..:.:|           |..::. :|::.|.:
  Fly   401 YLSQSQGA-------------PLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLS-NTMSANLS 451

Mouse   158 -----------GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQN 211
                       .|:.|.:|..::.||:..|||.|...:||....|.::|:||.:||.|:|:||||
  Fly   452 QSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQN 516

Mouse   212 RRMKWKKDH 220
            ||.||:|.|
  Fly   517 RRTKWRKRH 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		28/158 (18%)
		Antp-type hexapeptide	140..145		2/15 (13%)
		Homeodomain	162..218	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		1/2 (50%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	21/116 (18%)
		Homeodomain	465..523	CDD:459649	26/57 (46%)