Protein Alignment Hoxb4 and C15

DIOPT Version :10

• Sequence 1: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Sequence 2: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 185
• Identity: 58/185 - (31%)
• Similarity: 82/185 - (44%)
• Gaps: 36/185 - (19%)

Mouse    86 PGLSPRAPVQPTAGALLPEPGQRSEAVSSSPPPPPCAQNPLHPSPSHSACKE--PVVYPWMRKVH 148
            |.|.|.|    ..|.:|..|.||:....:.||..       |.:.:|.|.|:  ...:|..|::.
  Fly   153 PHLYPSA----AGGHVLRVPPQRTPLTWALPPLH-------HAALAHQAVKDRLAAAFPIARRIG 206

Mouse   149 VSTVNPNYAGGEPKRS--RTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQN 211
                :|......|||.  ||::||.||.||||.||..:||....|..:|..|.:::.|:|.||||
  Fly   207 ----HPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQN 267

Mouse   212 RRMKWKK--------DHKLPNTKIRSGGTAGAAGG--PPGRP-------NGGPPA 249
            ||.||::        :.:..|..:.|......:.|  ||..|       ||.|.|
  Fly   268 RRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLA 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		12/46 (26%)
		Antp-type hexapeptide	140..145		1/4 (25%)
		Homeodomain	162..218	CDD:459649	29/57 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		10/40 (25%)
C15	NP_476873.2	COG5576	<196..315	CDD:227863	39/122 (32%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)