Protein Alignment Hoxb4 and exex

DIOPT Version :10

• Sequence 1: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 106/462 - (22%)
• Similarity: 129/462 - (27%)
• Gaps: 270/462 - (58%)

Mouse    18 PPCEEYSQ----------SDYLP------------------SDHSPGYYAGGQRRESGFQPEAAF 54
            ||.::|.|          |...|                  |.::|....||.:..|  |.|:..
  Fly    50 PPAQDYDQGSNQSTLSPRSQITPSPPAASPTHSAATTGSPVSTYTPALSPGGAQDSS--QTESGQ 112

Mouse    55 GRRAPCTVQRYAACRDPGPP---PPPP---------PPP---PPPPPGLS----PRAPV------ 94
            ..:.|..|.....  ..|||   ||||         |||   |.|.|.|.    ||.|:
  Fly   113 SSQMPLLVAPMPV--GTGPPHSHPPPPHPRLYVEGFPPPHHVPHPHPALGTYPLPRLPLMLPANP 175

Mouse    95 ---------------QPTA------GA------LLPEPGQ------------------------- 107
                           ||.|      ||      ||| |.|
  Fly   176 PGVPSGAAAPPPVSPQPAANHLSHSGATMATTTLLP-PAQSQPKKSFCIDALLAKSQHQSGEPQP 239

Mouse   108 ----------------------------------------------------------------- 107
                                                                             
  Fly   240 IIVDDRLAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISEQEALQRIRDSREYDSPSPDG 304

Mouse   108 --RSEAVS----SSPP-PPPC--AQNP---LHP-------SPSHSACKEPVVYPWMRKVHVSTVN 153
              |||:.:    |||| .|.|  .|.|   |||       |..|...|:|:      ..| |.:.
  Fly   305 MSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPI------PPH-SPIR 362

Mouse   154 PN----YAGGEP----------------------------------------------------- 161
            |.    ||||.|
  Fly   363 PQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPEL 427

Mouse   162 ------------KRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRM 214
                        :|.|||:|.||:|||||:|..|:||:|.:|.|:|..|.|||.|:|||||||||
  Fly   428 AAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRM 492

Mouse   215 KWKKDHK 221
            |||:..|
  Fly   493 KWKRSKK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		57/303 (19%)
		Antp-type hexapeptide	140..145		0/4 (0%)
		Homeodomain	162..218	CDD:459649	36/55 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		1/3 (33%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	36/55 (65%)