DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and CG34367

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_001097140.1	Gene:	CG34367 / 5740879	FlyBaseID:	FBgn0085396	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	78/347 - (22%)
Similarity:	124/347 - (35%)	Gaps:	110/347 - (31%)

- Green bases have known domain annotations that are detailed below.

Mouse    63 HAKSKELNGSCMRPGLAPEP----------LPAPPGSPPPSAAPTSTTSNSNNGGGPSKSGPPKC 117
            |.::..|:.:..:..:.|:|          :.:.|..|..|..||::.:              :|
  Fly    98 HVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASIT--------------EC 148

Mouse   118 GAGSNSTLTKQIFPWMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGD 182
            ...||                |.||....|...|.|
  Fly   149 TEDSN----------------TPKLAPDKPLLPEEC----------------------------- 168

Mouse   183 KSPPGS---------------AASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSE 232
            .||..|               ...:|:||.:|..||.|||:.|....|.....|.|::..|.|||
  Fly   169 VSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSE 233

Mouse   233 RQIKIWFQNRRMKYKK--DQKAKGLASSSGGPSPAGSPPQPMQSTAGFMN--ALHSMT-PSY--- 289
            .::::||||||.|.:|  :|..||....|..| |..:|.:|.: .|.:::  ||.|.: ||:
  Fly   234 ARVQVWFQNRRAKCRKHENQMHKGFLVGSRSP-PIATPLEPCR-VAPYVSLAALRSSSVPSHPAA 296

Mouse   290 -DSPSPPAFG------KGHQNAYALPSNYQPPLKGCGAPQKYPPTPA-----SEYEPHVLQANGG 342
             .|.:|.|.|      .|.......|.|:.|.:.. .|.:::..|.|     |.::|.::.....
  Fly   297 ATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISR-SAIKQFSSTVAAAAAFSAFDPAIISVAAH 360

Mouse   343 AYGTPTMQGSPVYVGGGGYADP 364
            .|......|:   |..|.::.|
  Fly   361 QYAAAITNGT---VPAGLFSVP 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124		12/70 (17%)
		Antp-type hexapeptide	129..134		0/4 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		10/73 (14%)
		Homeobox	195..248	CDD:365835	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		8/26 (31%)
		DUF4074	369..431	CDD:372548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433
CG34367	NP_001097140.1	Homeobox	195..248	CDD:278475	23/52 (44%)
CG34367	NP_001097140.1	OAR	392..409	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910