Protein Alignment Hoxb3 and E5

DIOPT Version :9

• Sequence 1: NP_001073338.1
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 102/463 - (22%)
• Similarity: 145/463 - (31%)
• Gaps: 176/463 - (38%)

Mouse    13 ALFGGYSSYPGSNGFGYDGPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPG 77
            ||.|..:| |.:......|||.||.|....|...:|.:|.       .|.|.:.::.......|
  Fly   167 ALIGNRTS-PNAMAVRMAGPPHPPSQPPPFLAAQFQMAAA-------LAHHHQQQQQQQQQQLP- 222

Mouse    78 LAPEPLP-APPGSP----PPSAAPTSTTSNSNNGGGPSKSGPPKCG---AGSNSTLTKQ---IFP 131
                |:| .||..|    ||...|.....     |||....||..|   .||...|.:.   ::|
  Fly   223 ----PVPTGPPHGPHPHLPPGQIPLGIFP-----GGPHPGHPPPHGHHPFGSAPHLIRDSYPLYP 278

Mouse   132 WMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSP--PGS------ 188
            |:. ||.                                          |...|  ||:
  Fly   279 WLL-SRH------------------------------------------GRIFPRFPGNFLFQPF 300

Mouse   189 AASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAK 253
            ...||.|||::..||::||..|..|.|:....|.::|..|:|:|.|:|:||||||.|:|:.|:..
  Fly   301 RKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEG 365

Mouse   254 GLAS---SSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPA------------------F 297
            |..|   |:.|.|..|......:..|....:.|    ||:....|.                  :
  Fly   366 GDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQH----SYEDAEDPEDEDEIEEDDEDEVIDMDDY 426

Mouse   298 G-----KGHQNAYALPSNYQPPLKGCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVG 357
            |     :.||.   |...:|..|              ::::...:|.|.|.
  Fly   427 GSEMDAEEHQR---LREQFQQQL--------------AQHQQQFMQQNAGE-------------- 460

Mouse   358 GGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQG 422
                                              ||.:.|.|.|.....|..:.. ..||...|.
  Fly   461 ----------------------------------AATLSPQQQHQLLQQHQQHLQ-QQHHQQQQH 490

Mouse   423 RIQEAPKL 430
            .||:..:|
  Fly   491 FIQQQQQL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		18/68 (26%)
		Antp-type hexapeptide	129..134		2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		8/66 (12%)
		Homeobox	195..248	CDD:365835	24/52 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		7/29 (24%)
		DUF4074	369..431	CDD:372548	12/62 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433		12/42 (29%)
E5	NP_524825.1	Homeobox	307..359	CDD:278475	24/51 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000