Protein Alignment Hoxb3 and Dfd

DIOPT Version :9

• Sequence 1: NP_001073338.1
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 129/579 - (22%)
• Similarity: 168/579 - (29%)
• Gaps: 282/579 - (48%)

Mouse     6 YYDNTA-----AALFGGYSSYPGSNGFGYDGPPQPPF---QAATHLEGDYQRSACSLQSLGNAAP 62
            ::.|:|     .|..|||||     .:....||..|.   .|..|            ||||....
  Fly   110 HHSNSAISGHHQASAGGYSS-----NYANATPPSHPHSHPHAHPH------------QSLGYYVH 157

Mouse    63 HAKSKELNGSCMRPGLAPEPLPAPPGSPPPSAAPTSTTSNSNNGGGPSKSGPPKCGAGSNSTLTK 127
            |               |||.:.|           .:..|:..||.||:.
  Fly   158 H---------------APEFISA-----------GAVHSDPTNGYGPAA---------------- 180

Mouse   128 QIFPWMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGG----------- 181
                             :.|.|:.|.||||.|...|||..|||:.|..||.|||
  Fly   181 -----------------NVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGST 228

Mouse   182 ----------------------------------------------------------------- 181
                                                                             
  Fly   229 HSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMG 293

Mouse   182 --------------DKSP----------------------------------------------- 185
                          |:||
  Fly   294 SENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANG 358

Mouse   186 ---PGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYK 247
               || ...||.|||||..|::|||||||:||||.|.||:|:|:.|.||||||||||||||||:|
  Fly   359 SYQPG-MEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWK 422

Mouse   248 KDQK-------AKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAFGKGHQNAY 305
            ||.|       .|....::|.|:|...                       .|:..|..|..|.|.
  Fly   423 KDNKLPNTKNVRKKTVDANGNPTPVAK-----------------------KPTKRAASKKQQQAQ 464

Mouse   306 ALPSNYQPPLKGCGAPQKYPPTPASE--YEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPP 368
            ....:.|         |:...||...  .....|::.|   ...:..|:|.|:       |..|.
  Fly   465 QQQQSQQ---------QQTQQTPVMNECIRSDSLESIG---DVSSSLGNPPYI-------PAAPE 510

Mouse   369 AGPSLYG-LNHLSHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQGRIQE 426
            ...|..| ..|||     |.:.||:.....|.::...:.:....:....|....|.:|:
  Fly   511 TTSSYPGSQQHLS-----NNNNNGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQ 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		10/60 (17%)
		Antp-type hexapeptide	129..134		0/4 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		27/198 (14%)
		Homeobox	195..248	CDD:365835	39/52 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		6/33 (18%)
		DUF4074	369..431	CDD:372548	12/59 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433		6/38 (16%)
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	39/51 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810