DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and bcd

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_788587.1	Gene:	bcd / 40830	FlyBaseID:	FBgn0000166	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	63/248 - (25%)
Similarity:	89/248 - (35%)	Gaps:	71/248 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse   192 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYK------KDQ 250
            :|.||.:||:|:.|||:.|...|||..||..:::..|.|...|:||||:|||.::|      |||
  Fly    98 RRTRTTFTSSQIAELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQ 162

Mouse   251 KAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAFGKGHQNAYALPSNYQPPL 315
            ..:|:..|.|.....|.||.....:.|     ...||:..:|||.
  Fly   163 SYEGMPLSPGMKQSDGDPPSLQTLSLG-----GGATPNALTPSPT-------------------- 202

Mouse   316 KGCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYAD-------PLPPPAGPSL 373
                     |.||.:....|..::....|.         |.||..:|.       ..|...||.
  Fly   203 ---------PSTPTAHMTEHYSESFNAYYN---------YNGGHNHAQANRHMHMQYPSGGGPG- 248

Mouse   374 YGLNHLSHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQGRIQE 426
                      .|:.:.||.......|.|.    |........:|.|.|.:.|:
  Fly   249 ----------PGSTNVNGGQFFQQQQVHN----HQQQLHHQGNHVPHQMQQQQ 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124
		Antp-type hexapeptide	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		1/2 (50%)
		Homeobox	195..248	CDD:365835	25/58 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		8/26 (31%)
		DUF4074	369..431	CDD:372548	12/58 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433		9/38 (24%)
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	21/46 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900