DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and zen2

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	58/170 - (34%)
Similarity:	77/170 - (45%)	Gaps:	43/170 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   188 SAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKA 252
            |..|||:|||::|.||:|||:|||.|:||.|.||:|::..|.|:|||:||||||||||.||....
  Fly    40 SEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKSTNR 104

Mouse   253 KGLASSSGGPSPAGS-PPQPMQ-----------------STAGFMNALH------SMTPSYDSPS 293
            ||...:.....|..| ..:.:|                 .||......|      .:||.|.|
  Fly   105 KGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVLEEGQITPPYQS-- 167

Mouse   294 PPAFGKGHQNAYALPSNYQPPLKGCGAPQKYPPTPASEYE 333
                       |.....:.|      .|...|..|.:|::
  Fly   168 -----------YDYLHEFSP------EPMALPQLPFNEFD 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124
		Antp-type hexapeptide	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		4/6 (67%)
		Homeobox	195..248	CDD:365835	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		5/44 (11%)
		DUF4074	369..431	CDD:372548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	34/52 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770